AI Medical Compendium

Hypergraph-Based Dual-Channel Improved Variational Autoencoder with Cross-Attention for Compound-Protein Interactions Identification.

Journal of chemical information and modeling May 4, 2026

Elucidating compound-protein interactions is crucial for early drug discovery, offering insights into molecular mechanisms and therapeutic potential. While wet-lab methods detect interactions, they suffer from false positives, high costs, and labor i... read more

Augmented Reality and Artificial Intelligence for the Assessment and Rehabilitation of Spatial Neglect: A Systematic Review.

Neurorehabilitation and neural repair May 4, 2026

BACKGROUND AND PURPOSE: Augmented reality (AR) and artificial intelligence (AI) have been applied to the assessment and rehabilitation of post-stroke spatial neglect (SN). This study aims to evaluate the feasibility, effectiveness, degree of personal... read more

Modeling pH-Dependent Protein Dynamics by Integrating Coarse-Grained Molecular Simulation and the Deep Neural Network Model.

Journal of chemical theory and computation May 4, 2026

The pKa values of titratable residues are fundamental parameters that shape protein behavior in a given solution environment. They govern electrostatic interactions and thereby influence protein folding, conformational dynamics, and molecular recogni... read more

Machine Learning Accelerates Crystallization for Structure Determination.

Angewandte Chemie (International ed. in English) May 4, 2026

Single-crystal x-ray diffraction (SCXRD) is a powerful tool for structural elucidation, but requires high-quality crystals that are often difficult to obtain. The crystalline mate strategy helps overcome this limitation by facilitating the co-crystal... read more

The role of AI in prostate cancer care: Assessing the role of chatbots versus urologists in patient communication and empathy.

Urologia May 4, 2026

OBJECTIVE: To date, the integration of artificial intelligence (AI) in healthcare has expanded rapidly, offering new tools for patient education and communication. In prostate cancer (PCa), where information needs are high and emotionally sensitive, ... read more

An AI-Ready Phosphorylation Meta-Analysis for Saccharomyces cerevisiae.

Journal of proteome research May 4, 2026

We, the PTMeXchange Consortium, present a meta-analysis of eight high-quality data sets to map 56,694 phosphosites in brewer's yeast (Saccharomyces cerevisiae) using strict control for false identifications. Each site has been classified into the Gol... read more

AIBAN-AI Bronchial Detection and Airway Navigation System.

Journal of bronchology & interventional pulmonology May 4, 2026

BACKGROUND: Accurate navigation within the lungs is critical for bronchoscopy procedures but remains challenging due to the complex airway anatomy. Artificial intelligence (AI) integrating real-time landmark detection and navigation guidance may enha... read more

MLN2SVG: domain-aware spatially variable gene detection using contrastive variational autoencoder and multi-level neighbor search.

Briefings in bioinformatics May 4, 2026

Spatial transcriptomics (ST) technologies have transformed our ability to examine gene expression within intact tissues, yet accurately identifying spatially variable genes (SVGs) remains challenging due to spatial heterogeneity, data sparsity, and i... read more

Comprehensive evaluation of artificial intelligence-empowered approaches for protein-aptamer complex prediction.

Briefings in bioinformatics May 4, 2026

Drug discovery is a time-consuming, expensive, and high-risk process. Recent advances in artificial intelligence (AI) have enabled major breakthroughs in small-molecule and protein therapeutics. However, AI-driven design of aptamer drugs remains larg... read more

Optimisation Drift and Substitution Risk in Artificial Intelligence-Supported Personalised Mental Health Nursing: A Critical Synthesis on Therapeutic Presence and Care Biography.

Journal of psychiatric and mental health nursing May 4, 2026

INTRODUCTION: Artificial intelligence-supported personalisation is accelerating in mental health services, yet it can reclassify relationship, biography, and judgement as optional. AIM/QUESTION: To explain how "personalisation" drifts into substituti... read more

Artificial Intelligence Medical Compendium