Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 23,061 to 23,070 of 216,842 articles

Spatiotemporal single-cell atlas of suture stem cell dynamics in craniosynostosis.

Stem cell research & therapy May 3, 2026
BACKGROUND: Craniosynostosis is a congenital disorder characterized by premature suture fusion and aberrant skull morphogenesis. The cellular dynamics and regulatory mechanisms of suture mesenchymal stem cells (SuSCs) in this disease remain poorly de... read more 

Reconstruction of Molecular Interaction Patterns from Endolysosomes in Ceramide-Depleted Cells.

Nano letters May 3, 2026
Ceramide synthase (CerS) is a key enzyme in sphingolipid metabolism, predominantly maintaining lipid homeostasis within the endoplasmic reticulum (ER). Capturing the biochemical consequences of CerS activity at the subcellular level is of great inter... read more 

Development and validation of a machine learning-based screening tool for early detection of adolescent suicide risk.

Journal of child psychology and psychiatry, and allied disciplines May 3, 2026
BACKGROUND: Adolescent suicide remains a significant public health concern, yet existing suicide screening instruments primarily focus on already manifested suicidal phenomena, underscoring the need for reliable and practical tools to enable early id... read more 

HighFold-MeD2: An Enhanced Boltz-2 Model for Accurate Structure Prediction of N-Methylated and d-Amino Acid Cyclic Peptides.

Journal of chemical information and modeling May 3, 2026
Cyclic peptides containing backbone N-methylated amino acids (BNMeAAs) and d-amino acids (d-AAs) exhibit exceptional metabolic stability, membrane permeability, and oral bioavailability, representing a pivotal middle space scaffold between biologics ... read more 

Exploring the Potential of the PerioAI System to Support Periodontal Clinical Decision Making: A Proof-of-Principle Study.

Journal of clinical periodontology May 3, 2026
AIM: To explore the potential of PerioAI, an artificial intelligence system integrating intraoral scanning and cone-beam CT, to automatically measure gingival margin-to-bone distance (GBD) and convert it into AI-derived probing depth (AI-PD), and to ... read more 

An unsupervised framework for comparing SARS-CoV-2 protein sequences using LLMs

bioRxiv May 3, 2026
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic led to 700 million infections and 7 million deaths worldwide. While studying these viruses, scientists developed a large amount of sequencing data that was made available to re... read more 
bioinformatics

Molecular insights into protein disulfide isomerase antagonism by punicalagin

bioRxiv May 3, 2026
Punicalagin, an ellagic acid polyphenol from pomegranate, has been proposed as an antagonist of protein disulfide isomerase (PDI) and endoplasmic reticulum resident protein 57 (ERp57), thiol oxidoreductases that regulate protein folding and extracell... read more 
biochemistry

Agentic systems are adept at solving well-scoped, verifiable problems in computational biology

bioRxiv May 3, 2026
We introduce CompBioBench, a benchmark of 100 diverse tasks for evaluating agentic systems in computational biology. Unlike mathematics and programming, which more readily admit systematic verification, biological data are inherently noisy and open t... read more 
bioinformatics

Predicting first-onset depression in adolescents: Do general population models generalize to youth with ADHD?

medRxiv May 3, 2026
Background: Most studies seeking to identify youth at increased risk for depression have developed prediction models using a limited set of risk factors in general population samples. It is unclear whether these models generalize to high-risk youth. ... read more 
psychiatry and clinical psychology

Transforming Patient Voices into Early Predictors of Survival Using Nonlinear Mixed-Effect Models and AI/ML for Patient-Centered Decision-Making

medRxiv May 3, 2026
Patient-reported outcomes (PROs) capture the patient voice and have been associated with improved clinical outcomes in oncology, but their prognostic and predictive value remains underutilized due to challenges in interpreting these highly variable a... read more 
oncology
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