Optical Coherence Tomography (OCT) has become one of the most used imaging modality in ophthalmology. It provides high-resolution, non-invasive visualization of retinal microarchitecture. The automated analysis of OCT images through representation le... read more
The efficacy of deep neural networks is heavily reliant on the design of non-linear activation functions, yet existing approaches often struggle to balance optimization stability with computational efficiency. While piecewise linear functions offer i... read more
Artificial intelligence (AI) is becoming a clinical tool for prostate pathology, but generalization across variations in sample preparation and preservation over prolonged time periods remains poorly understood. We evaluated GleasonAI, an end-to-end ... read more
The lack of analytical models describing diffusion time dependence at intermediate time scales in complex tissue microstructure limits the accurate quantification of extracellular diffusivity and tissue microstructure. We introduce TRACED, a biophysi... read more
Preference optimization has become a central paradigm for aligning large language models with human feedback. Direct Preference Optimization (DPO) simplifies reinforcement learning from human feedback by directly optimizing pairwise preferences, remo... read more
Explicit reconstruction constraints derived from the decoupled representation are further imposed to suppress abnormal channel amplification and chromatic noise. Experiments on LOLv2-Real, MIT-Adobe FiveK, and LSRW show that the proposed method achie... read more
Vision-Language Models (VLMs) have enabled autonomous GUI agents that translate natural language instructions into executable screen coordinates. However, grounding performance degrades in high-resolution interfaces, where dense layouts and small int... read more
Predicting microsatellite instability (MSI) status from routine hematoxylin and eosin (H&E) whole slide images (WSIs) offers a practical alternative to molecular testing, but models trained at one institution tend to generalize poorly to slides acqui... read more
Optical coherence tomography (OCT), a commonly used retinal imaging modality, plays a central role in retinal disease diagnosis by providing high-resolution visualization of retinal layers. While deep learning (DL) has achieved expert-level accuracy ... read more
The advent of foundation models has heralded a new era in medical artificial intelligence (AI), enabling the extraction of generalizable representations from large-scale unlabeled datasets. However, current ophthalmic AI paradigms are predominantly c... read more
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