BACKGROUND: Knee osteoarthritis (OA) is a leading global cause of disability, yet conventional tools lack sensitivity for early detection and precise prognostication. Artificial intelligence (AI) and machine learning (ML) offer powerful means to enha... read more
BACKGROUND: As artificial intelligence (AI) becomes increasingly integrated into healthcare and nursing education, existing competency standards and training systems for clinical nursing educators are no longer sufficient to meet the demands of techn... read more
Autophagy is a self-digestive process in which cellular components are degraded and recycled to maintain homeostasis and cope with stress. When cells are in a state of stress, autophagy will degrade proteins, lipids and damaged organelles, and conver... read more
BACKGROUND: MicroRNA (miRNA) biomarker studies in Alzheimer's disease (AD) typically assume monotonic relationships between expression levels and disease status, overlooking the non-linear, context-dependent nature of miRNA regulatory networks. This ... read more
BACKGROUND: Alzheimer's disease (AD) is a progressive neurodegenerative disease. Traditional models for estimating AD onset cannot capture nonlinear interactions (epistasis) among the numerous genetic variables that contribute to AD risk. METHODS: We... read more
Wide-bandgap (WBG) lead halide perovskite materials are indispensable top-cell materials for tandem solar cells (TSCs), whose high power-conversion potential, tunable bandgaps, and solution processability dictate the efficiency ceiling and commercial... read more
Tomato yellow leaf curl virus (TYLCV) is among the most devastating pathogens affecting tomato production worldwide, with emerging virulent strains increasingly overcoming genetic resistance and triggering severe outbreaks. Traditional field diagnosi... read more
The blood - brain barrier (BBB) plays a central role in maintaining central nervous system (CNS) homeostasis, and its disruption is a defining feature of malignant brain tumors such as glioblastoma. Emerging evidence indicates that BBB dysfunction no... read more
British journal of clinical pharmacology
Apr 30, 2026
Medication-related problems (MRPs) place a substantial burden on the healthcare system, contributing to hospital admissions and significant healthcare costs. Quality prescribing indicators (QPIs), rules and criteria serve to educate prescribers about... read more
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