AI Medical Compendium

A prospective multimethod investigation of cancer-related pain integrating clinical data and machine learning: results from the RUGGI Study.

Journal of anesthesia, analgesia and critical care Apr 30, 2026

BACKGROUND: Cancer-related pain is a multidimensional phenomenon, and key determinants of pain intensity remain unclear. The aim of this study was to identify the clinical determinants of cancer-related pain intensity using a convergent, multimethod ... read more

Data-Driven Modeling of Composition-Processing-Microstructure Relations for Recycled Aluminum Cast Alloys.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Apr 30, 2026

Aluminum is the second most widely used metal worldwide, with essential roles in transportation, construction, packaging, and energy infrastructure. Recycling aluminum can save up to 95% of the energy required for primary production, making it a corn... read more

Mimetics of in-cell and subcellular crowding and solvation for protein folding.

Biochemical Society transactions Apr 30, 2026

Historically, fundamental principles of protein folding were extracted from dilute in vitro experiments that disregarded the complexity of the cell interior. It is now well-established that the cellular environment modulates protein behaviors. Discre... read more

Decoupling Intrinsic Molecular Efficacy From Platform Effects: An Interpretable Machine Learning Framework for Unbiased Perovskite Passivator Discovery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Apr 30, 2026

Rational design of interface passivators for perovskite solar cells is hindered by the entanglement of intrinsic molecular efficacy with extrinsic platform-dependent performance-a confounding factor that obscures true chemical advances. Here, we pres... read more

Current and Emerging Therapies Targeting the IL-23/IL-17 Axis in Psoriasis.

Biomolecules & therapeutics Apr 30, 2026

Over the past two decades, experimental and clinical evidence has established the interleukin-23 (IL-23)/interleukin-17 (IL-17) axis as a key mediator of psoriatic inflammation. IL-23, primarily derived from activated dendritic cells, supports the su... read more

Generative AI-Assisted Medical Illustrations in Pediatric Neurosurgery: Workflows, Ethical Safeguards, and Journal Policy Considerations.

Journal of Korean Neurosurgical Society Apr 30, 2026

Generative artificial intelligence (AI) has emerged as a transformative tool for creating high-quality visual materials in medical research and education. In pediatric neurosurgery, where ethical and legal constraints limit the use of real patient ph... read more

Large Language Model and Pediatric Neurosurgery - A Neurosurgeon's Perspective on the Artificial Nervous System.

Journal of Korean Neurosurgical Society Apr 30, 2026

Large language models (LLMs) are rapidly transforming healthcare, yet their implications for pediatric neurosurgery remain underexplored. This narrative review interprets LLM evolution through a neuroscientific lens familiar to pediatric neurosurgeon... read more

The challenge of bringing advances in sacroiliac joint imaging to the clinic.

Current opinion in rheumatology Apr 30, 2026

PURPOSE OF REVIEW: Recently reported criteria are more stringent for classification of axial spondyloarthritis (axSpA) in the absence of positive imaging. This places increased reliance on the accuracy of sacroiliac joint (SIJ) imaging. This review h... read more

Mechanistic Insights into PFAS Rejection in Nanofiltration and Reverse Osmosis from Data-Driven Analysis.

Environmental science & technology Apr 30, 2026

The structural diversity and complex transport behavior of per- and polyfluoroalkyl substances (PFAS) complicate a universal characterization of their removal in membrane systems. This study compiles 2353 data points from the literature on PFAS rejec... read more

Exploring the mechanisms and management of sepsis-related cardiac dysfunction.

Acta cardiologica Apr 30, 2026

Sepsis-related cardiac dysfunction (SRCD) represents a critical determinant of both acute mortality and long-term cardiovascular morbidity in sepsis survivors. Sepsis-related cardiac dysfunction denotes the spectrum of acute, non-ischemic myocardial ... read more

Artificial Intelligence Medical Compendium