Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 24,471 to 24,480 of 217,425 articles

Predicting Supramolecular Self-Assembly of Peptide Structures with AlphaFold3

bioRxiv Apr 30, 2026
Self-assembled peptide-based nanostructures have diverse applications in the pharmaceutical and materials fields, but accurately predicting their self-assembly behavior without time-intensive organic synthesis and characterization remains a significa... read more 
bioengineering

Species-specific transformer models of bacterial gene order and content for genomic surveillance tasks

bioRxiv Apr 30, 2026
Transformer models enable functionally meaningful representation of complex biological data, such as nucleotide or protein sequences. Existing foundation transformer models are trained on large multi-domain corpuses of unlabelled DNA or protein data,... read more 
bioinformatics

Automatic deep learning-based segmentation and quantification of stented arterial cross-sections for morphometric analysis

bioRxiv Apr 30, 2026
Arterial vascular diseases, such as atherosclerosis, are among the most serious global health threats. In preclinical studies, morphometric analysis of histological arterial cross-sections is considered the gold standard for assessing vascular remode... read more 
pathology

Systems Pharmacology Reveals Type I Interferon and Myeloid-Like B Cell Reprogramming as Druggable Axes in Antiphospholipid Syndrome

bioRxiv Apr 30, 2026
Antiphospholipid syndrome (APS) lacks targeted therapies beyond anticoagulation, and its molecular heterogeneity remains poorly characterized. We employed an integrative systems pharmacology approach combining weighted gene co-expression network anal... read more 
bioinformatics

Multidimensional Mechanistic Study of Panax Notoginseng Saponins in the Treatment of Alcohol-Induced Osteonecrosis of the Femoral Head: Integrating Network Pharmacology, Molecular Dynamics Simulation and In Vivo Validation

bioRxiv Apr 30, 2026
Background: Alcohol-induced osteonecrosis of the femoral head (AIONFH) is an orthopedic disorder from chronic alcohol abuse, characterized by disrupted femoral head blood supply, osteocyte death and structural collapse. Current hip-preserving therapy... read more 
pharmacology and toxicology

EnzCast: Prediction of Patient-Specific Enzymatic Kinetics through Multi-Modal Deep Learning and Isoform-Resolved Bayesian Inference based on Single-Cell Transcriptomics

bioRxiv Apr 30, 2026
Enzyme kinetic parameters underpin mechanistic biology but remain sparse in physiological context. We present EnzCast, a multi-modal framework jointly predicting Km, kcat, kcat/Km, and Ki from protein sequence, 3D structure, substrate chemistry, and ... read more 
bioinformatics

Predicting Phage Host Interactions Across Taxonomic Levels: A Systematic Review and Meta-Analysis for Microbial Ecology

bioRxiv Apr 30, 2026
The prediction of phage-host interactions is key for several applications in biotechnology, medicine, and microbial ecology. Wide studies in machine learning tools have allowed the exploration of these interactions across multiple taxonomic levels. A... read more 
microbiology

Graph-based learning and read-out of nanopore translocation event signals

bioRxiv Apr 30, 2026
Nanopores enable single-molecule analysis by measuring current signals through nanoscale pores in either biological or solid-state membranes. Accurate detection of analyte fingerprints within the pore environment is essential for reading-out the anal... read more 
bioengineering

Programming Biomolecular Interactions with All-Atom Generative Model

bioRxiv Apr 30, 2026
Biomolecular interactions lie at the core of cellular life, spanning diverse molecular modalities from small molecules to nucleic acids and proteins. Nevertheless, design strategies remain separated despite shared physicochemical principles of molecu... read more 
bioengineering

Population geometry reveals directed coupling and transient bistability in spontaneous pituitary secretion

bioRxiv Apr 30, 2026
The pituitary gland operates as an organized signaling network in which endocrine cell populations coordinate hormone secretion, through homotypic and heterotypic interactions, yet the contribution of spontaneous intrinsic activity in shaping populat... read more 
neuroscience
Popular Topics
Recent Journals