Journal of molecular graphics & modelling
Apr 29, 2026
Accurate drug-target affinity (DTA) prediction is pivotal for virtual screening, yet practical reliability is often limited by the static treatment of molecular interactions and the "black-box" nature of deep learning models. In biological reality, b... read more
OBJECTIVES: Studies have investigated the potential applications of Large Language Models (LLMs) in dental education. As LLMs evolve, it is necessary to determine the extent to which their accuracy improves before they can be integrated into dental c... read more
Theta burst stimulation (TBS) is a promising form of repetitive transcranial magnetic stimulation (rTMS) capable of modulating cortical excitability and intracortical processes, offering therapeutic potential for neurological and psychiatric disorder... read more
MOTIVATION: Zebrafish embryo assays are increasingly recognized as a robust and scalable model for developmental toxicity screening due to embryos' optical transparency, rapid organogenesis, and high genetic and physiological conservation with humans... read more
International journal of pharmaceutics
Apr 29, 2026
Polymer-based long-acting injectables (LAIs) have transformed the treatment of chronic diseases by enabling controlled drug delivery, thus reducing dosing frequency and extending therapeutic duration. Achieving controlled drug release from LAIs requi... read more
Soil microbiomes are increasingly recognized as valuable indicators in forensic investigations, but microbial dynamics in mass graves remain poorly understood. This study investigates differences in microbial succession between individual graves (IG)... read more
Rapid eye movement (REM) sleep behaviour disorder (RBD), particularly its idiopathic/isolated form (iRBD), is a prodromal marker for α-synucleinopathies, including Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. Machine le... read more
BACKGROUND: To understand the molecularly obscure pre-diagnostic phase of lung cancer, we mapped the temporal evolution of the plasma proteome for new biological insights and improved risk prediction. METHODS: Leveraging the UK Biobank prospective co... read more
Machine-generated music (MGM) has become a groundbreaking innovation with wide-ranging applications, such as music therapy, personalised editing, and creative inspiration within the music industry. However, the unregulated proliferation of MGM presen... read more
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