Artificial Intelligence Medical Compendium

Activity-based protein profiling has identified hundreds of human proteins from diverse classes that react at cysteine residues with stereochemically defined electrophilic compounds (stereoprobes). The structure-activity relationships underlying thes... read more 

Cervical cancer remains a leading cause of cancer-related mortality among women globally, with persistent high-risk human papillomavirus (HPV) infection as the primary etiological factor. Cervical precancerous lesions, including high-grade squamous i... read more 

Studies applying artificial intelligence (AI) to tuberculosis (TB) detection from chest radiographs (CXR) focus on models and metrics, yet the quality, provenance and reproducibility of the data workflow decide the reliability of results; duplicate i... read more 

To test whether anatomical priors from a general-purpose organ segmentation model (TotalSegmentator, TS), applied at inference or during training, improve an externally validated YOLOv11 detector for six acute abdominal emergencies. The frozen detect... read more 

Accurate assessment of different types of prostate cancer (PCa) lesions is a crucial part of treatment planning. Following a computed tomography (CT) or a positron emission tomography (PET)/CT imaging scan, a significant amount of time is required fr... read more 

As the evening sets in and natural light fades to artificial light, it is remarkable how the colors around us still appear nearly the same. This phenomenon, known as color constancy, allows us to perceive relatively stable colors even as lighting con... read more 

Long non-coding RNAs (lncRNAs) play a pivotal role in regulating biological processes, primarily through lncRNA-Protein Interactions (LPI), which are crucial for understanding disease mechanisms and cellular functions. While computational methods exi... read more 

RéSUMé: CONTEXTE: Les grands modèles de langage (LLM) sont de plus en plus utilisés par les patients et les cliniciens pour obtenir des informations médicales, mais leurs performances peuvent évoluer au fil du temps à mesure que les modèles sont mis ... read more 

The rapidly global deployment of COVID-19 mRNA-LNP vaccines established the clinical feasibility of combining RNA medicine with LNP delivery systems, transforming a long-standing experimental concept into a scalable therapeutic modality, previously c... read more 

Laboratories that move from GRCh38 to T2T-CHM13 take on a new callset as well as a new assembly. I asked whether the move changes sex-chromosome genotype summaries, and whether it changes how well classifiers trained on those summaries serve males an... read more