Artificial Intelligence Medical Compendium

Explore the latest research on artificial intelligence and machine learning in medicine.

Showing 25,021 to 25,030 of 217,472 articles

Integrating high-fidelity hiPSC-cardiomyocytes with AI-driven modeling for enhanced proarrhythmic risk assessment.

Archives of toxicology
Cardiotoxicity remains the leading driver of drug attrition; however, its prediction remains suboptimal when conventional hERG assays and animal models are used. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) offer a human-rel... read more 

Single-cell chromatin accessibility and cis-regulatory element analyses in plants using the scPlantReg platform.

Nature plants
Understanding gene regulation is fundamental to plant improvement. However, the lack of plant-specific single-cell assay for transposase-accessible chromatin using sequencing (scATAC-seq) frameworks and cross-species databases has limited insights in... read more 

BrainFusionNet: a deep learning and XAI model to understand local, global, and sequential features of MRI images for improved brain tumour detection.

Brain informatics
The noise of Magnetic Resonance Imaging (MRI) poses challenges for Deep Learning (DL) when tumor boundaries are obscured, tumor location and appearance are complex due to overlap between tumor and non-tumor cells, and modality identification is diffi... read more 

Computational insights into drug hygroscopicity by coupling machine learning and molecular simulation.

Drug delivery and translational research
Hygroscopicity is one of the critical material attributes (CMAs) of active pharmaceutical ingredients (APIs), and excessive hygroscopicity can adversely affect drug manufacturability, stability, and even therapeutic efficacy. Traditional experimental... read more 

A deep learning method for children's self-care problems classification using represent learning and focal loss.

Technology and health care : official journal of the European Society for Engineering and Medicine
BackgroundAn accurate diagnosis of children's self-care problems significantly matters in the growth and development of children. However, various and extensive disorders make the self-care problems classification extremely complex and require much e... read more 

A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery.

Nature biotechnology
Lipid nanoparticle (LNP) delivery of RNA therapeutics is constrained by poor tissue selectivity and off-target toxicity. Most high-throughput screening approaches have focused on single-target efficacy while overlooking off-target uptake. Here we rep... read more