Melanocytes become cancerous, forming tumors that may invade and destroy the surrounding tissues. When melanocytes acquire invasive characteristics, the anchored melanoma begins to damage the normal cells. Therefore, early intervention and diagnosis ... read more
Background Timely detection is crucial to improve outcomes in patients with cardiac amyloidosis (CA) by initiation of life-saving treatments. Although confirmatory bone scintigraphy is highly accurate for CA detection, identifying at-risk patients fo... read more
Poxviruses constitute a threat to human health. Since 2022, two public health emergencies of international concern due to global spread of mpox viruses (MPXVs) were declared. The emergence of the novel MPXV subclade Ib has placed the global health co... read more
Introduction Despite the proven benefits of reperfusion therapies in acute ischemic stroke, treatment decisions in the hyperacute phase remain complex and are rarely supported by individualized outcome predictions. Artificial intelligence (AI)-based ... read more
We present a suite of foundational, outcome prediction models for critically ill patients, developed using readily available, routine blood tests and advanced machine learning techniques. The input data of the models includes complete blood counts (C... read more
Background & Aims: Accurate assessment of clinical malnutrition using anthropometric and functional indicators could improve the care of elderly trauma patients in intensive care units (ICUs). This study aimed to develop an AI-driven malnutrition ass... read more
Background Polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs) are combustion-derived pollutants linked to cardiovascular disease. Prior NHANES analyses have evaluated these chemicals individually, failing to capture the cor... read more
Traditionally, studies have explored the impacts of individual water chemistry parameters on the persistence of Mycobacterium spp. and Legionella spp. in isolation with the underlying assumption that these associations are likely monotonic in nature.... read more
Diffuse Large B-cell lymphoma (DLBCL) is the most common aggressive lymphoma in the Western world. First-line immunochemotherapy fails in approximately 30-40% of patients, with refractory and relapse patients presenting a dismal prognosis. Currently,... read more
Background: Prognostication after moderate-to-severe traumatic brain injury (TBI) rarely captures long-term functional recovery, despite its importance to patients, families, and clinicians. Large trauma registries such as the Trauma Quality Improvem... read more
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