Spatial Transcriptomics (ST) technology detects gene expression from tissue biopsies, playing an emerging role in cancer diagnosis and precision medicine. However, the high cost of ST technology limits its broader application. Recently, deep learning... read more
IEEE journal of biomedical and health informatics
Apr 28, 2026
Deep neural networks have achieved strong performance in medical image segmentation when the training and testing data share similar appearance characteristics. However, this assumption is rarely satisfied in practical clinical scenarios, where imagi... read more
IEEE journal of biomedical and health informatics
Apr 28, 2026
OBJECTIVE: The diagnosis of Sleep Apnea-Hypopnea Syndrome (SAHS) holds significant importance for assessing sleep quality and treating sleep disorders. However, the detection of hypopnea events has not been given due emphasis, and the precise delinea... read more
Recurrent neural networks (RNNs) with predefined-time convergence capabilities are among the most powerful solvers for time-varying zero-finding problems (TVZFPs). However, a comprehensive design framework for such neural networks has not yet been we... read more
Annual review of biomedical data science
Apr 28, 2026
The vast potential of observational healthcare data in biomedical discovery remains largely unrealized because clinical records are fragmented, unstructured, and generated for patient care rather than research. Clinical knowledge representation (KR) ... read more
BACKGROUND: Ulcerative colitis (UC) exhibits substantial heterogeneity in inflammatory pathways and therapeutic response. The organic cation transporter OCTN1 (SLC22A4) and its rs1050152 missense variant (L503F) have been implicated in innate immune ... read more
INTRODUCTION: Intravenous thrombolysis (IVT) with tissue-type plasminogen activator (tPA) is a cornerstone of acute ischemic stroke treatment, yet its benefits are limited by the risk of symptomatic intracranial hemorrhage (sICH), a complication asso... read more
BACKGROUND: Social media use has become pervasive among university students worldwide, with growing evidence linking excessive use to negative psychological and academic outcomes. While various scales exist to assess problematic social media use, mos... read more
BACKGROUND: Fatal and non-fatal drug overdoses have evolved into a critical public health crisis, with over a 50% increase in the rate of fatal drug overdose since 2019. Emergency Medical Services (EMS) data has advantages over traditional emergency ... read more
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