Purpose: To develop an interpretable feature-based Deep Parametric Response Mapping (PRMD) method that combines wavelet scattering convolution networks and machine learning to spatially detect and quantify functional small airways disease (fSAD) and ... read more
Background. Foundation models for electronic health records (EHRs) perform strongly on clinical prediction, but every published model has been trained within a single health system. No multi-institutional EHR foundation model currently exists, largel... read more
Background Although Kenya's HIV programme has long prioritized high-burden counties for intensified paediatric interventions, a critical evidence gap remains in developing integrated analytic frameworks that can objectively predict and validate paedi... read more
Background. Studies applying machine learning to obsessive-compulsive disorder (OCD) typically report accuracy in homogeneous samples but rarely assess model reliability, generalizability, and interpretability needed for clinical use. Methods. We app... read more
Chronic psychological stress contributes to allostatic load and is associated with cardiovascular, metabolic, and mental health disorders. Wearable devices enable continuous, noninvasive monitoring of autonomic signals such as heart rate variability ... read more
Objective To develop and evaluate a novel machine learning (ML) framework tailored to a clinical diabetes dataset and to assess whether demographic stratification enhances model performance and interpretability for multiclass diabetes classification.... read more
Introduction Despite the proven benefits of reperfusion therapies in acute ischemic stroke, treatment decisions in the hyperacute phase remain complex and are rarely supported by individualized outcome predictions. Artificial intelligence (AI)-based ... read more
We present a suite of foundational, outcome prediction models for critically ill patients, developed using readily available, routine blood tests and advanced machine learning techniques. The input data of the models includes complete blood counts (C... read more
Background & Aims: Accurate assessment of clinical malnutrition using anthropometric and functional indicators could improve the care of elderly trauma patients in intensive care units (ICUs). This study aimed to develop an AI-driven malnutrition ass... read more
Background Polycyclic aromatic hydrocarbons (PAHs) and volatile organic compounds (VOCs) are combustion-derived pollutants linked to cardiovascular disease. Prior NHANES analyses have evaluated these chemicals individually, failing to capture the cor... read more
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