This study investigates the relationship between the gut microbiota and specific diseases. Data was collected from the Human Gut Microbiome Atlas, which examines regional variations across 20 countries on five continents, categorizing microbial speci... read more
Cardiotoxicity remains a major cause of drug attrition and post-market withdrawal, yet the vast majority of environmental chemicals to which humans may be exposed remain uncharacterized for cardiotoxicity risk. Human induced pluripotent stem cell (hi... read more
Space-biology imaging studies are often constrained by severe data scarcity, limiting the development of robust machine-learning biomarkers. Rodent spaceflight and space-analog datasets provide an important preclinical setting for testing transfer-le... read more
The molecular characterization of human solid growths has introduced immense genomic complexity and intra-tumoral diversification. Converting these detailed, multi-omic profiles right into workable, broad-spectrum therapeutics continues to be an awes... read more
Background: Radiographic detection of caries lesions adjacent to restorations is challenging due to limitations of two-dimensional imaging and difficulties distinguishing true lesions from restorative or anatomical radiolucencies. Artificial intellig... read more
Importance: Physicians routinely prognosticate to guide care delivery and shared decision making, particularly when caring for patients with critical illnesses. Yet, these physician estimates are prone to inaccuracy and uncertainty. Artificial intell... read more
Despite the remarkable progress of artificial intelligence represented by large language models, how AI technologies can contribute to the construction of evidence in evidence-based medicine (EBM) remains an overlooked issue. Now, we need an AI that ... read more
Background Outcome after stroke varies according to stroke subtype by location, but healthcare systems data studies do not include subtyping information. We linked natural language processing (NLP) of brain imaging reports to routinely collected data... read more
Sepsis is a leading cause of in-hospital mortality, yet systematically evaluating temporal adherence to the Surviving Sepsis Campaign (SSC) bundle across large patient populations remains difficult due to semantic variability in electronic health rec... read more
Tuberculosis (TB) is prevalent in Uganda and overlaps with a high rate of HIV/TB coinfection. While nearly all hospital-based TB cases in Kampala, the capital of Uganda, show clear TB symptoms, 30% or more of undiagnosed TB cases found through active... read more
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