AI Medical Compendium

Machine learning-based prediction of impaired arginine vasopressin secretion during hypertonic saline test.

Endocrine journal Apr 25, 2026

Hypertonic saline infusion and water deprivation tests are commonly used to stimulate arginine vasopressin (AVP) for the diagnosis of AVP deficiency (AVP-D); however, these procedures impose a considerable burden on patients. We aimed to develop mach... read more

Longitudinal assessment of chorea in Huntington's disease using digital passive monitoring.

NPJ digital medicine Apr 25, 2026

Chorea is a hallmark of Huntington's disease (HD), yet its clinical assessment is of limited reliability, impairing our ability to sensitively evaluate its progression. We evaluated passive monitoring for estimating the two-year evolution of upper li... read more

AI-driven quantum chemical exploration of multi-target synthetic opioid analogs for enhanced therapeutic profiles.

Journal of computer-aided molecular design Apr 25, 2026

Forest carbon stock estimation in a mountainous region using locally adaptive machine learning approaches.

Environmental monitoring and assessment Apr 25, 2026

Accurate estimation of forest carbon stocks is essential for climate change mitigation, particularly in mountainous regions where strong spatial heterogeneity constrains the performance of conventional remote sensing models. This study investigates w... read more

Artificial intelligence in neurofibromatosis type I: diagnostic and therapeutic opportunities.

Journal of applied genetics Apr 25, 2026

Enhancing genomic prediction for key production traits in chickens through ultrasound phenotyping and multi-model comparative analysis.

Journal of animal science and biotechnology Apr 25, 2026

BACKGROUND: Growth performance and carcass traits are economically vital in poultry breeding. In Wenchang chickens, reducing excessive abdominal fat represents a critical breeding objective. However, as a typical carcass trait, abdominal fat thicknes... read more

Neural posterior estimation for population genetics.

Genetics Apr 25, 2026

Simulation-based inference methods are increasingly being used in population genetics due to their flexibility and ability to be applied in settings where likelihood-based methods are intractable. Perhaps the best known such method is Approximate Bay... read more

Atomic clarity: how structural biology is shaping blood-stage malaria vaccines.

Transactions of the Royal Society of Tropical Medicine and Hygiene Apr 25, 2026

Developing an effective malaria vaccine is challenging because Plasmodium parasites use complex strategies to invade host cells. The blood stage, where parasites replicate inside red blood cells, causes disease symptoms and relies on large multiprote... read more

Opportunities and challenges related to participant stratification and cohort enrichment in ALS clinical trials.

Amyotrophic lateral sclerosis & frontotemporal degeneration Apr 25, 2026

Amyotrophic lateral sclerosis (ALS) is marked by substantial clinical heterogeneity. This heterogeneity has impacted clinical trials by obscuring treatment effects and causing inefficiency. In this review, we summarize potential approaches for addres... read more

Performance of a residual neural network system versus dental technicians for gingival porcelain shade matching.

Journal of prosthodontics : official journal of the American College of Prosthodontists Apr 25, 2026

PURPOSE: This study aimed to compare the accuracy of a residual neural network (ResNet) system with experienced dental technicians for gingival shade prediction. MATERIALS AND METHODS: CIELab (L*, a*, b*) coordinates were measured from three adjacent... read more

Artificial Intelligence Medical Compendium