Journal of chemical information and modeling
Apr 24, 2026
We present a unique, multitask data set comprising 143 drug and drug candidate molecules, each evaluated on in vitro parallel artificial membrane permeability assays (PAMPA) using six different model membranes. Using this resource, we systematically ... read more
Lynch syndrome (LS) is the most common hereditary colorectal cancer (CRC) syndrome and is characterized by an accelerated adenoma-carcinoma sequence, a relatively higher prevalence of flat and subtle CRC precursor lesions, and exceptionally high aden... read more
PURPOSE: To test inter-observer variation of plus disease diagnoses among Norwegian ophthalmologists and treatment centres. METHODS: All ophthalmologists in Norway who make individual retinopathy of prematurity (ROP) treatment decisions were invited ... read more
Angewandte Chemie (International ed. in English)
Apr 24, 2026
Magnesium batteries are compelling post-lithium energy storage candidates but suffer from sluggish charge transfer kinetics, fundamentally restricted by the high energy barrier of Mg2+ desolvation. Herein, we address the compact and tenacious solvati... read more
Angewandte Chemie (International ed. in English)
Apr 24, 2026
Infrared nonlinear optical (NLO) materials are essential for laser and photonic technologies, limited by fragmented material systems, lengthy development cycles, and trial-and-error synthesis. To overcome these barriers, we developed an integrated co... read more
BACKGROUND: Breast arterial calcification (BAC) detected on routine mammography is an emerging marker of cardiovascular risk in women. However, substantial age-related variability limits its clinical interpretability. Age-adjusted nomograms may impro... read more
BACKGROUND: Familial Hemiplegic migraine (FHM) is a rare migraine subtype characterised by transient unilateral motor weakness. Although familial forms are associated with variants in CACNA1A, ATP1A2, and SCN1A genes, many cases remain genetically un... read more
Higher-order genetic interactions have profound implications for understanding the molecular mechanisms of phenotypic variation, yet they remain poorly characterized. Most studies focus on pairwise interactions because high-throughput screens over th... read more
BACKGROUND: Peak oxygen consumption (peak VO2), the gold standard measure of cardiorespiratory fitness, may identify women at high risk for pregnancy-related cardiovascular (CV) complications, but ascertainment is not widely scalable. We previously d... read more
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