BACKGROUND: Psychogenic erectile dysfunction (pED) is a prevalent male erectile dysfunction without organic causes, and difficulties in erection attainment and post-penetration maintenance often co-occur. Although neuroimaging studies have implicated... read more
Acute pancreatitis (AP) lacks effective therapies, and excessive programmed cell death (PCD) drives its pathogenesis. This study identified cathepsin B (CTSB) as a core PCD regulator in AP via bioinformatics and animal experiments. Gene Expression Om... read more
INTRODUCTION AND AIMS: To develop and validate an AI-automated system for dental charting that accounts for multiple radiograph types and younger patients. METHODS: A total of 3705 dental radiographs were collected in Slovakia and Egypt between 2023 ... read more
International journal of medical informatics
Apr 26, 2026
INTRODUCTION: Generative artificial intelligence (GenAI) such as ChatGPT, is increasingly used to generate research ideas, aid in literature reviews, and support clinical reasoning. While its adoption is rapidly growing worldwide, concerns persist re... read more
Microplastics (MPs) are increasingly recognized as emerging contaminants in the human diet, yet the absence of unified biomarker-anchored screening thresholds hampers quantitative risk assessment. This study establishes a gut microbiota-anchored mach... read more
Ovarian cancer (OC) remains therapeutic challenge due to its complex molecular heterogeneity and therapy-induced adaptive resistance. While non-apoptotic cell death and senescence pathways contribute to tumor evolution and immunosuppression, their in... read more
Environmental organic pollutants, identified as Polycyclic Aromatic Hydrocarbons (PAHs), are widespread and toxic. These hydrocarbons are commonly produced by industrial activities, burning fossil fuels, and crude oil discharges. Their high hydrophob... read more
Pediatric hydrocephalus is commonly assessed on computed tomography (CT) using manual two-dimensional indices that incompletely reflect the ventricular system. We developed and evaluated an explainable, segmentation-free three-dimensional convolution... read more
Understanding the spatial mechanisms of multi-enzyme lignocellulose deconstruction is hindered by the lack of spatial quantification and nondestructive analytical methods. This study established an interpretable three-dimensional (3D) deep learning f... read more
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