AI Medical Compendium

MMP9 in macrophages: A pivotal biomarker associated with immune dysregulation in interstitial cystitis/bladder pain syndrome.

Urologia Apr 24, 2026

BACKGROUND: Studies suggest that immune abnormalities play a significant role in the pathophysiology of interstitial cystitis/bladder pain syndrome (IC/BPS), yet reliable targets and biomarkers for immune intervention remain unidentified. The aim of ... read more

Identification of PANoptosis-Related Biomarkers in Head and Neck Squamous Cell Carcinoma.

Oral diseases Apr 24, 2026

BACKGROUND: The early detection and diagnosis of head and neck squamous cell carcinoma (HNSCC) pose significant challenges. OBJECTIVES: This study explores the diagnostic and prognostic role of PANoptosis-related genes (PANRGs) in HNSCC. METHODS: In ... read more

In Silico Prediction of Potential Bile Salt Export Pump Inhibitors Using Pharmacophore Models and Consensus Machine Learning.

Journal of chemical information and modeling Apr 24, 2026

The ATP-dependent bile salt export pump (BSEP) is a transporter responsible for moving bile salts from hepatocytes into bile canaliculi. Inhibition of BSEP is a known risk factor of cholestatic-drug-induced liver injury (DILI) probably caused by the ... read more

Nanointerface-Engineered Triboelectric Nanocomposite for Self-Powered Intelligent Motion Decoding.

ACS applied materials & interfaces Apr 24, 2026

Real-time motion intelligence from wearable systems requires efficient conversion of biomechanical energy into stable and information-rich electrical signals. However, conventional triboelectric sensors often suffer from limited interfacial polarizat... read more

Rega: A Platform for the Prediction of the Regioselectivity of C-H Functionalization Reactions.

Journal of chemical information and modeling Apr 24, 2026

Sulfinate-mediated radical C-H functionalization reactions are widely used for the modification and diversification of scaffolds in drug discovery. There may be multiple sites of reaction, each with a unique steric and electronic environment. Here we... read more

Responsible AI Integration Framework for Psychiatric Guidelines.

The international journal of neuropsychopharmacology Apr 24, 2026

Artificial intelligence (AI) is reshaping medicine, promising advances in diagnosis, monitoring, and treatment, and psychiatry will be no exception. Yet the field remains fragmented: ethical guidelines, technical standards, and clinical workflows hav... read more

Uncovering the Global Burden and Future Trajectories of Nanomagnetite Particle Emissions from Biomass Power Plants.

Environmental science & technology Apr 24, 2026

Biomass power plants (BPPs) are expanding rapidly, yet the most toxicologically potent nanoscale fraction of its particulate emissions remains poorly quantified. Here, in vitro assays demonstrate that nanomagnetite particles (NMPs) constitute a dispr... read more

Generalizable spinal cord multiple sclerosis lesion segmentation across MRI contrasts, protocols, and centers.

Multiple sclerosis (Houndmills, Basingstoke, England) Apr 24, 2026

BACKGROUND/OBJECTIVES: Characterizing spinal cord multiple sclerosis (MS) lesions in MRI is critical for diagnosis, monitoring, and treatment evaluation. However, current automated approaches for lesion detection and segmentation are typically design... read more

Identification and multi-layered experimental validation of feature genes related to butyrate metabolism and oxidative stress in sepsis.

Artificial cells, nanomedicine, and biotechnology Apr 24, 2026

The mechanisms underlying sepsis remain poorly understood and specific therapeutic options remain lacking. Accumulating evidence suggests that butyrate metabolism and oxidative stress (OS) are involved in the pathogenesis of sepsis. This study aims t... read more

Creating gerotechnologists: a call to action for university-based collaboration bridging gerontology and engineering.

Gerontology & geriatrics education Apr 24, 2026

This paper urges universities to form interdisciplinary partnerships between gerontology and engineering programs to develop curricula, mentor students, train faculty, and engage in community outreach. The goal is to equip gerontologists and engineer... read more

Artificial Intelligence Medical Compendium