AI Medical Compendium

Cerebellar gray matter volume difference in first-episode bipolar and unipolar depression.

BMC psychiatry Apr 22, 2026

BACKGROUND: Early differential diagnosis of bipolar disorder (BD) and unipolar depression (UD) remains a major clinical challenge, especially during the initial depressive episode. This study aimed to investigate whether cerebellar gray matter volume... read more

Long COVID: Deep single-cell immunophenotyping and machine learning reveal a general signature for fatigue.

Journal of translational medicine Apr 22, 2026

Predicting amyotrophic lateral sclerosis stage based on multi-parameter ultrasound: development and validation of an interpretable machine learning model.

BMC medicine Apr 22, 2026

BACKGROUND: Amyotrophic lateral sclerosis (ALS) lacks sensitive, objective staging tools to guide clinical management and trials. Existing methods have limited granularity and rely on subjective assessment, while biomarker and imaging approaches can ... read more

Modelling the epidemic dynamics of HPV among women in China and optimization of ongoing cervical cancer elimination strategies.

BMC medicine Apr 22, 2026

BACKGROUND: The infection of high-risk human papillomavirus (hr-HPV) and related cervical cancer have greatly threatened women's health. However, the benefits of ongoing strategies in China remains unclear. Insufficient vaccine supply and excessive s... read more

Dysfunction of the neurovascular unit as a temporal driver in Alzheimer's pathogenesis.

Translational neurodegeneration Apr 22, 2026

Extensive studies have shown that cerebrovascular dysfunction is a critical factor in the onset and progression of Alzheimer's disease (AD). Neurovascular unit (NVU) is impaired in AD brains, including damage of tight junction between endothelial cel... read more

Accelerating sow nursing behavior monitoring with modified YOLO11n architecture and TensorRT integration.

Porcine health management Apr 22, 2026

Machine learning predictions surpass individual mRNAs as a proxy of single-cell protein expression.

Genome biology Apr 22, 2026

BACKGROUND: Expansive repositories of scRNA-seq data are now available. These are often analysed assuming that mRNA abundance reflects expression of the cognate protein. However, post-transcriptional/translational regulation and the sparsity of measu... read more

eDNA and AI Identification Reveal Complementary Signals in Phytoplankton Monitoring.

Environmental science & technology Apr 22, 2026

Phytoplankton regulates aquatic energy transfer and biogeochemical cycling, yet accurately characterizing community composition remains challenging because different monitoring methods capture complementary but incomplete signals. Here we present a c... read more

Association of epigenetic trajectory with development of clinical rheumatoid arthritis in anti-citrullinated protein antibody positive individuals: Targeting Immune Responses for Prevention of Rheumatoid Arthritis (TIP-RA).

Arthritis & rheumatology (Hoboken, N.J.) Apr 22, 2026

OBJECTIVE: The presence of anti-citrullinated protein antibodies (ACPAs) in the absence of clinical inflammatory arthritis (IA) identifies individuals at risk for rheumatoid arthritis (RA). We examined whether epigenetic remodeling of DNA methylation... read more

Performance assessment of five artificial intelligence-based algorithms for automated tooth segmentation and labeling on intraoral scans.

Journal of prosthodontics : official journal of the American College of Prosthodontists Apr 22, 2026

PURPOSE: This study aimed to evaluate and compare the performance of five AI algorithms for tooth segmentation and labeling on intraoral scans, as their performance remains unclear. MATERIALS AND METHODS: A total of 100 intraoral scans in the STL fil... read more

Artificial Intelligence Medical Compendium