Monte Carlo simulations are widely used to simulate complex molecular systems, but standard approaches suffer from metastability. Lately, the use of nonlocal proposal updates in a collective-variable (CV) space has been proposed in several works. Her... read more
In our previous work, we developed a CCSD(T)-level range-separated water force field that combines the power of physics-driven and machine learning models. However, it was found that expensive CCSD(T)/CBS calculations lead to a limited number of QM d... read more
Graphene oxide (GO) exhibits rich chemical heterogeneity that strongly influences its structural, thermal, and mechanical properties, yet quantitatively linking reduction chemistry to heat transport remains challenging. In this study, we develop a ma... read more
PURPOSE: Despite recent advances in preoperative work-up of drug resistant medial temporal lobe epilepsy (MTLE), predicting post-surgical seizure and memory outcomes remains challenging. Differentiating between "no hippocampal sclerosis Gliosis Only"... read more
Many existing studies on federated learning (FL) for segmentation primarily assume that all client data are labeled. However, in reality, due to the high cost of hospital construction and the scarcity of expert annotators, many medical sites can only... read more
OBJECTIVES: To develop and validate a deep learning model for automatic segmentation of pulmonary masses on apparent diffusion coefficient (ADC) maps and to assess repeatability of automated ADC quantification. METHODS: We proposed ADCSegNet, a deep ... read more
Bioinformatics has transformed modern virology by linking genomic variation to epidemiology, protein structure, and public health action. This review integrates core analytical frameworks-sequence alignment and genome annotation; maximum-likelihood a... read more
The World Allergy Organization journal
Apr 21, 2026
BACKGROUND: The exact molecular mechanisms governing a heightened risk of chronic spontaneous urticaria (CSU) associated with autophagy remain largely unexplored. METHODS: We used the GSE72540 RNA dataset (human biopsy samples) for CSU as our trainin... read more
Journal of oral biology and craniofacial research
Apr 21, 2026
BACKGROUND: Oral squamous cell carcinoma (OSCC) remains a leading cause of cancer-related morbidity and mortality worldwide. The ability to detect early histopathological evidence of invasion-particularly basement membrane (BM) discontinuity at the e... read more
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