Rational design of covalent inhibitors requires simultaneously optimizing multiple properties, such as binding affinity, target selectivity, or electrophilic reactivity. This presents a multi-objective problem not easily addressed by screening alone.... read more
As microelectronics flourish and outsourcing of the design and manufacturing stages of integrated circuits (ICs) and printed circuit boards (PCBs) becomes the norm, microelectronics stakeholders must also confront a new wave of security challenges, i... read more
Large language models are increasingly deployed as autonomous diagnostic agents, yet they conflate two fundamentally different capabilities: natural-language communication and probabilistic reasoning. We argue that this conflation is an architectural... read more
For state-of-the-art image understanding, Vision Transformers (ViTs) have become the standard architecture but their processing diverges substantially from human attentional characteristics. We investigate whether this cognitive gap can be shrunk by ... read more
Automated bacterial colony counting from images is an important technique to obtain data required for the development of vaccines and antibiotics. However, bacterial colonies present unique machine vision challenges that affect counting, including (1... read more
Recent advances in text-guided image editing and 3D Gaussian Splatting (3DGS) have enabled high-quality 3D scene manipulation. However, existing pipelines rely on iterative edit-and-fit optimization at test time, alternating between 2D diffusion edit... read more
Journal of the Pediatric Orthopaedic Society of North America
Apr 21, 2026
BACKGROUND: Spinopelvic assessment is critical for surgical planning. It is unknown if age, sex, and body mass index (BMI) influence pelvic orientation during development. This study aimed to (1) describe normative pelvic orientation and (2) investig... read more
BACKGROUND: Efforts to ameliorate the current organ shortage have predominantly focused on improving processes among the nation's organ procurement organizations. However, there is no consensus on how to measure the quality of an individual hospital'... read more
Spatial memory is a fundamental cognitive capacity governing the mental encoding of spatial information, which can be used to navigate through intricate terrains. While most navigation models rely on place- and grid cells as key building blocks, in f... read more
Sclerotinia sclerotiorum causes Sclerotinia stem rot, or white mold, on multiple economically important crops in Michigan. Soybean farmers and crop consultants in the midwestern United States currently use S. sclerotiorum apothecia prediction models ... read more
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