Journal of chemical information and modeling
Apr 20, 2026
The transmembrane complex formed by TREM2 (Triggering Receptor Expressed on Myeloid cells 2) and DAP12 (DNAX-activating protein of 12 kDa) constitutes a pivotal therapeutic target for Alzheimer's disease. However, the intrinsic plasticity of its inte... read more
Journal of the American Chemical Society
Apr 20, 2026
Atomic structure analysis of crystalline materials is a paramount endeavor in both chemical and material sciences. This sophisticated technique necessitates not only a solid foundation in crystallography but also a profound comprehension of the intri... read more
Clinical and translational gastroenterology
Apr 20, 2026
INTRODUCTION: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects up to 30% of the global population and drives progression to fibrosis, cirrhosis, and liver cancer, yet early-stage identification remains limited by subjective hi... read more
STUDY OBJECTIVES: To develop and evaluate artificial intelligence methods for detecting upper-body joint positions from video recordings of individuals during sleep, providing a foundation for future automated, video-based analysis of sleep movements... read more
Neural network architecture determines its functional output. However, the detailed mechanisms are not well characterized. In this study, we focused on the neural network architectures of male and hermaphrodite Caenorhabditis elegans and the associat... read more
Rapid and precise discrimination of Escherichia coli strains─including both pathogenic and nonpathogenic variants─is essential for clinical diagnosis and food safety monitoring. Raman spectroscopy provides nondestructive molecular fingerprint informa... read more
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and m... read more
Advanced materials (Deerfield Beach, Fla.)
Apr 20, 2026
The discovery of novel organic optoelectronic materials for applications such as organic light-emitting diodes, organic photovoltaics, and organic field-effect transistors has traditionally been constrained by the inefficiency of trial-and-error expe... read more
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