Breast cancer prognosis and treatment outcomes are shaped by intricate interplay between tumor biology, systemic comorbidities, and patient-reported functional status. This paper introduces a framework to address critical gaps in precision oncology b... read more
BACKGROUND: Predicting disease progression at the individual level is essential for personalized medicine. We previously developed machine-learning tools to estimate 5-year progression risk in people with multiple sclerosis (PwMS). Such models should... read more
BACKGROUND: Accurate prediction of pathological complete response (pCR) after preoperative chemoradiation therapy, followed by surgery (trimodality therapy) in esophageal adenocarcinoma (EAC) and gastroesophageal junction adenocarcinoma (GEJAC) may i... read more
The growing demand for biopharmaceutical products reflects their effectiveness in medical treatments. However, developing new biopharmaceuticals remains a major bottleneck, often taking up to a decade before market approval. Machine learning (ML) mod... read more
Journal of magnetic resonance imaging : JMRI
Apr 19, 2026
BACKGROUND: Poor cardiac MR image quality can prompt repeat examinations and hinder clinical decision-making. PURPOSE: To evaluate whether pre-imaging clinical information, extracted using a large language model (LLM), is independently associated wit... read more
The integration of measurable residual disease (MRD) into the management of chronic lymphocytic leukemia (CLL) has emerged as a major advance in risk stratification and trial design, particularly in the context of time-limited, targeted regimens. Hig... read more
Organophosphate flame retardants (OPFRs), as emerging substitutes for halogenated flame retardants, are widely detected in populations and pose global health concerns. However, their structural diversity and expanding numbers challenge conventional e... read more
The current scientific ecosystem is characterized by a systemic crisis driven by the Publish or Perish culture and an exponential growth in publication volumes that outpaces the number of active researchers. Here, we highlight the limitations of trad... read more
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