Predicting which receptor a phage binds to from genome sequence alone has remained an intractable challenge, principally because the experimental phenotypic data required to train and validate predictive models have not been available at sufficient s... read more
BackgroundPredicting whether a treatment will demonstrate meaningful clinical benefit before committing to a large-scale trial remains a major unmet need in oncology. Patient-derived organoids (PDOs) recapitulate individual tumor drug sensitivity, bu... read more
Abstract Background Diabetic Retinopathy (DR) is one of the leading cause of vision loss and blindness. AI models have been instrumental in providing an alternative solution to real-life medical treatment which are costly and sometimes not readily av... read more
International journal of food microbiology
Apr 18, 2026
Spoilage microorganisms and pathogenic bacteria can negatively impact food safety and stability, leading to potential health risks and economic losses. Predictive microbiology is a crucial tool for forecasting microbial behavior in food matrices, and... read more
Biochemical and biophysical research communications
Apr 18, 2026
OBJECTIVE: This study aims to delineate the molecular mechanisms through which aristolochic acid (AA) exposure drives renal cell carcinoma (RCC) pathogenesis, leveraging an integrated machine learning (ML) and multi-omics approach to systematically i... read more
The AIXA Osteo model architecture (X1AI-Osteo) has undergone internal validation in Taiwan, demonstrating its capability to evaluate osteoporosis and predict T-scores reliably. Nonetheless, its efficacy in alternative clinical environments has not be... read more
Early detection and prevention of chicken disease are crucial for the sustainability of the poultry industry. However, early identification is often hindered by environmental noise and disease-specific acoustic feature extraction. This study proposes... read more
Journal of the American College of Emergency Physicians open
Apr 18, 2026
OBJECTIVES: Acute kidney injury (AKI) is a common and serious condition associated with prolonged hospitalization, chronic kidney disease, and increased mortality. Early prediction of AKI offers an opportunity to mitigate these adverse outcomes, yet ... read more
Microplastics (MPs) are increasingly detected in freshwater ecosystems, yet the factors influencing their bioaccumulation in fish, particularly in reservoir systems, remain insufficiently understood. We investigated MPs bioaccumulation in 150 individ... read more
OBJECTIVES: To develop a deep learning-based multi-class segmentation model for the simultaneous segmentation of key periodontal structures, including enamel, cementum, alveolar bone, and gingiva, in ultrasound images, and to enable precise localizat... read more
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