INTRODUCTION: Unstructured clinical data, including operative reports and progress notes, contain critical surgical information that is often absent from structured electronic health record fields. Manual abstraction is time-consuming at scale. Natur... read more
Brain age is a valuable neuroimaging-based biomarker for assessing brain health, typically estimated using machine learning (ML) models. However, ML approaches suffer from inherent bias, requiring post-hoc correction, and may mask age-related biologi... read more
Diabetic Kidney Disease (DKD) is strongly related to ferroptosis, an iron-dependent form of programmed cell death characterized by the accumulation of lipid peroxides. While ferroptosis is a pivotal mediator in DKD pathogenesis, its upstream regulato... read more
Survival prognosis is crucial for medical informatics. Practitioners often confront small-sized clinical data, especially cancer patient cases, which can be insufficient to induce useful patterns for survival predictions. This study deals with small ... read more
Personal history of migration poses an important risk factor for schizophrenia spectrum disorders (SSD), which are also associated with a higher rate of criminal behavior. To enhance care for migrants, a vulnerable and often stigmatized group in both... read more
PURPOSE: This study systematically evaluated five deep learning models to validate their consistency in deriving clinical morphological and quantitative digital subtraction angiography (QDSA) hemodynamic biomarkers. METHOD: In this dual-center retros... read more
Computer methods and programs in biomedicine
Apr 18, 2026
BACKGROUND AND OBJECTIVE: Tumor-infiltrating lymphocytes (TILs) are an important indicator of immune activity in breast cancer, yet scoring them consistently on H&E slides remains challenging in routine pathology. This work presents a modular deep le... read more
Precise detection of amino acids is critical for proteomics and molecular recognition. Nanopore sensing enables label-free single-molecule analysis but often lacks sufficient spatial resolution to control translocation dynamics and resolve protein st... read more
International journal of ophthalmology
Apr 18, 2026
AIM: To develop an automated diagnostic system for early detection of diabetic retinopathy (DR) using fundus images by identifying exudates, hemorrhages, and microaneurysms with advanced image processing and machine learning techniques. METHODS: Fund... read more
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