Atmospheric haze significantly degrades wildlife imagery, impeding computer vision applications critical for conservation, such as animal detection, tracking, and behavior analysis. To address this challenge, we introduce AnimalHaze3k a synthetic dat... read more
BACKGROUND: Tertiary lymphoid structures (TLS) are ectopic lymphoid formations within or around tumours. They are emerging as important predictors of prognosis and response to immune checkpoint inhibitors (ICIs) in various cancers. However, in Merkel... read more
We present an optically gated thin-film transistor sensor that distinguishes chemicals through illumination-induced transient electrical responses. The device consists of a p-type silicon substrate with native oxide and an amorphous Ge2Se3 photogatin... read more
INTRODUCTION: Optimizing multidrug regimens for complex diseases remains a major challenge in precision medicine because responses are shaped by interpatient heterogeneity, nonlinear drug interactions, and incomplete mechanistic knowledge. Phenotypic... read more
While most children recover from pediatric "mild" traumatic brain injury (pmTBI), up to one-third experience persisting symptoms after concussion (PSaC) that interfere with school, social, and emotional functioning. Clinicians face the dual challenge... read more
Digital assays have become a state-of-the-art technology for the sensing of nucleic acid molecules. Nevertheless, most of the prevalent digital nucleic acid assays heavily rely on sealed microchambers and sophisticated nucleic acid amplification stra... read more
Journal of chemical information and modeling
Apr 17, 2026
Genetic mutations in the transcription factor FOXP1 (forkhead box protein P1) cause an autosomal dominant neurodevelopmental disorder called FOXP1 syndrome. To understand the structural impact of pathogenic variants associated with FOXP1 syndrome, we... read more
Understanding transplantation outcomes requires an integrated view of immunological, genetic, and clinical determinants that collectively shape graft function over time. Although HLA mismatches are primary drivers of graft injury, emerging evidence h... read more
Platelets are small, anucleate cells with a primary physiological role in vascular damage repair (hemostasis) and initiation of thrombus formation in response to vascular injury. Platelets circulate approximately 7-10 days, slowly undergoing age-rela... read more
Given the unclear pathogenesis and insidious progression of Alzheimer's disease (AD), the aim of the present study was to identify reliable diagnostic markers for AD detection using a combination of bioinformatics analysis, animal experiments and cli... read more
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