AI Medical Compendium

Indispensable tools of critical care management: blood gas analyzers.

Scandinavian journal of clinical and laboratory investigation Apr 17, 2026

Blood gas analysis remains one of the most indispensable diagnostic tools in critical care, yet increasing automation often obscures its analytical foundations and limitations. This review provides an integrated perspective by tracing the evolution o... read more

Incorporating artificial intelligence into morphological diagnosis of acute leukemias: Current landscape, challenges and prospects (Review).

Oncology reports Apr 17, 2026

Acute leukemias (ALs) are a diverse group of hematological malignancies characterized by the abnormal proliferation of immature cells. Microscopic observation of cell morphology based on the French‑American‑British classification remains a fundamenta... read more

Novel therapeutic strategies for metastatic castration‑resistant prostate cancer: Beyond androgen receptor pathway inhibition (Review).

International journal of oncology Apr 17, 2026

Metastatic castration‑resistant prostate cancer (mCRPC) remains a lethal disease due to universal resistance to androgen‑receptor pathway inhibitors (ARPI). Tumor progression is orchestrated by a spectrum of androgen‑receptor‑independent drivers, inc... read more

NetMHCIIphosPan: A Machine Learning Tool for Predicting HLA Class II Antigen Presentation of Phosphorylated Peptides.

Journal of proteome research Apr 17, 2026

Phosphorylated peptides presented by human leukocyte antigen (HLA) class II molecules play pivotal roles in immune regulation, yet their characterization and prediction remain challenging due to data noise and limited HLA coverage. Here, we introduce... read more

Explainable Machine Learning Guided Enhanced Sampling of Protein Conformational Transition in HSP90.

Journal of chemical theory and computation Apr 17, 2026

Elucidating the thermodynamics, kinetics, and mechanisms of protein conformational transitions remains a longstanding challenge in molecular dynamics simulations. We employ enhanced sampling simulations using explainable machine-learning (ML)-based c... read more

Application of an open-source AI tool for quantitative quality control in whole slide images of prostate needle core biopsies - a retrospective study.

Journal of histotechnology Apr 17, 2026

The quality of Whole Slide Images (WSI) is a determining factor for proper diagnosis and prognosis, and for enhanced performance of Digital and Computational Pathology. In a context where diagnoses are increasingly quantitative, an automated, precise... read more

Evaluation of AI-Generated Surgical Decision Aids for Pelvic Floor Disorders.

Urogynecology (Philadelphia, Pa.) Apr 17, 2026

IMPORTANCE: Decision aid tools are well-utilized resources in shared decision making for the treatment of pelvic floor disorders. With the improvement of large language models like ChatGPT, prior studies have started evaluating whether artificial int... read more

Machine Learning-Driven Ensemble Screening of Multitarget Kinase Inhibitors for Tauopathy-Associated Neurodegeneration Using All-Atom and Steered MD Simulations.

ACS chemical neuroscience Apr 17, 2026

Tauopathies arise when normal functions of the tau protein in axonal transport and neuronal maintenance are disrupted by an imbalance between kinases and phosphatases. Dysregulation of key kinases such as dual-specificity Tyrosine-Regulated Kinase 1A... read more

DANCE: Deep Learning-Assisted Analysis of ProteiN Sequences Using Chaos Enhanced Kaleidoscopic Images.

Journal of computational biology : a journal of computational molecular cell biology Apr 17, 2026

Cancer is a complex disease characterized by uncontrolled cell growth and requires an accurate classification for effective treatment. T cell receptors (TCRs), crucial proteins in the immune system, play a pivotal role in antigen recognition. Advance... read more

Plasmonic hot-electron-assisted ultra-stretchable hydrogel electrodes for wearable cardiovascular monitoring and AI-driven predictive analytics.

Journal of materials chemistry. B Apr 17, 2026

Wearable bioelectronic systems require soft, deformable materials that maintain high electrical conductivity and reliable interfacial charge transport under large mechanical strains. However, most existing hydrogel- or elastomer-based conductors invo... read more

Artificial Intelligence Medical Compendium