AI Medical Compendium

Chiral Fluorescent Carbon Dots as Multi-Phased Sensors for Hg2+, Pd2+, and Cysteine Enantiomers.

Analytical chemistry Apr 16, 2026

This work presents a novel chiral fluorescence sensor for the selective and sensitive detection of mercury (Hg2+) and palladium (Pd2+) ions and an enantioselective detection of L/D-cysteine based on fluorescence turn off in the presence of Hg2+ and P... read more

Reimagining human-centric drug development with new approach methodologies.

Science (New York, N.Y.) Apr 16, 2026

Despite unprecedented technological progress, most drug candidates continue to fail in clinical trials, reflecting a persistent gap between preclinical models and human biology. New approach methodologies (NAMs), by spanning human-derived cellular sy... read more

Using technology to support children with dyscalculia in pre-primary and primary school: insights, challenges and opportunities.

Disability and rehabilitation. Assistive technology Apr 16, 2026

PURPOSE: Developmental Dyscalculia (DD) is a specific neurodevelopmental learning disability that significantly impairs an individual's ability to learn and process mathematical concepts. Given that preschool and primary school years represent critic... read more

Rise of AI Technologies in Virtual Screening.

Journal of chemical information and modeling Apr 16, 2026

AI foundational models for predicting protein-ligand interactions and binding affinities have started to emerge. We challenged Boltz-2 on a difficult data set constructed on ten ultralarge virtual screening hit lists of pharmacologically relevant tar... read more

Acceptance of Artificial Intelligence in Clinical Practice Among Chinese Physicians: Nationwide Cross-Sectional Survey Using Extended Unified Theory of Acceptance and Use of Technology and Explainable Machine Learning.

JMIR medical informatics Apr 16, 2026

BACKGROUND: Artificial intelligence (AI) is rapidly transforming clinical practice, yet empirical evidence on Chinese physicians' acceptance of AI medical tools remains scarce at the national level. OBJECTIVE: This study aimed to evaluate the current... read more

Targeted use of large language models for EHR-based computable phenotyping.

Journal of the American Medical Informatics Association : JAMIA Apr 16, 2026

OBJECTIVE: Computable phenotypes derived from electronic health records (EHRs) are central to clinical research and quality reporting. Although large language models (LLMs) can extract clinically rich information from unstructured notes, routine appl... read more

Planning in the Brain: It's Not What You Think It Is.

Annual review of neuroscience Apr 16, 2026

The neuroscience of planning has long been analogized to search algorithms in artificial intelligence (AI), which simulate future actions to guide immediate choices. We argue that advances in both neuroscience and AI suggest that planning is better u... read more

Automatic sleep staging from CPAP airflow using a dual fusion multi-period convolutional neural network.

Physiological measurement Apr 16, 2026

BACKGROUND: Continuous Positive Airway Pressure (CPAP) therapy is the standard treatment for obstructive sleep apnea-hypopnea syndrome, yet its use as a passive sleep dynamics monitoring remains limited. CPAP devices record only airflow signals, call... read more

Indocyanine green fluorescence for intraoperative detection of liver tumours in minimally invasive surgery: protocol for the LIVERGREEN phase IV multicentre clinical trial.

BMJ open Apr 16, 2026

INTRODUCTION: Liver tumours are a leading cause of global morbidity and mortality. Current diagnostic tools, including computed tomography (CT), magnetic resonance imaging (MRI) and intraoperative ultrasound (IOUS), have limitations in detecting live... read more

Circulating extracellular vesicle long RNA profiling combined with machine learning unveils novel diagnostic signature and molecular features in chronic pancreatitis.

Gut Apr 16, 2026

BACKGROUND: No clinically useful non-invasive biomarkers have been developed for diagnosis of chronic pancreatitis (CP), and molecular features of CP have not been characterised. Extracellular vesicles (EVs) consisted of abundant RNA species with spe... read more

Artificial Intelligence Medical Compendium