Journal of neurointerventional surgery
Apr 16, 2026
BACKGROUND: The early prediction of functional outcomes in patients with posterior circulation stroke (PCS) is crucial for timely interventions and optimizing treatment plans. We have developed and validated a machine learning (ML) model for predicti... read more
Journal of neurointerventional surgery
Apr 16, 2026
BACKGROUND: In an extended time window, contrast-based neuroimaging is valuable for treatment selection or prognosis in patients with stroke undergoing reperfusion treatment. However, its immediate availability remains limited, especially in resource... read more
RATIONALE: Despite significant advances in patient care and outcomes, criteria for cardiopulmonary exercise testing (CPET) in risk stratification guidelines for lung resection have not been updated in over a decade. We hypothesised that CPET no longe... read more
Predicting the risk of sleep disorders such as insomnia, obstructive sleep apnea (OSA), and comorbid insomnia and sleep apnea (COMISA) typically requires costly and time-consuming assessments. The SLEEPS algorithm simplifies this process using only n... read more
STUDY OBJECTIVES: Polysomnography (PSG) provides a comprehensive assessment of brain, cardiac, and respiratory activity during sleep. While it is widely used for diagnosing sleep disorders, its potential to assess future health risks has not been ful... read more
Quantitative features could help objectively identify and grade insomnia severity, though there is currently no pathophysiological biomarker of insomnia. In this study, we used the largest cohort of individuals with and without insomnia to date to tr... read more
Preclinical antibody discovery relies on progressive screening and down-selection of candidate antibodies from large immune repertoires, yet this critical process is poorly represented in existing public databases. Here we introduce KyDab (Kymouse An... read more
Transcription factors (TFs) are central regulators of gene expression, and their selective recognition of genomic DNA underlies various biological processes. Experimental profiling of TF -- DNA interactions using chromatin immunoprecipitation followe... read more
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