AI Medical Compendium

Dynamic changes in serum HER2-peptide-specific autoantibodies predict response to neoadjuvant therapy in HER2-positive breast cancer.

Breast cancer research : BCR Apr 15, 2026

Linking neurological status to functional outcomes in spinal cord injury: a multi-class, task-specific approach.

BMC biomedical engineering Apr 15, 2026

Magnetic resonance imaging-based radiomics of mesorectum for predicting extramural venous invasion in patients with rectal cancer: a bi-centric study.

Cancer imaging : the official publication of the International Cancer Imaging Society Apr 15, 2026

OBJECTIVES: To develop and validate a magnetic resonance imaging (MRI)-based radiomics model of the mesorectum for predicting extramural venous invasion (EMVI) in patients with rectal cancer (RC). METHODS: A retrospective study included 238 patients ... read more

ANNalog: generation of MedChem-similar molecules.

Journal of cheminformatics Apr 15, 2026

Generative deep learning models have demonstrated significant potential in designing drug-like molecules. However, medicinal chemistry typically requires generating analogues that combine structural similarity with scaffold hopping, which is the repl... read more

Where next for psychiatry: its past, present and future.

International review of psychiatry (Abingdon, England) Apr 15, 2026

Humanity is entering a new phase of social evolution with rapid digitalisation and increasing use of artificial intelligence in our lives. Psychiatric conditions also evolve with social changes. Like other branches of medicine, the management of psyc... read more

From Atoms to Fragments: A Coarse Representation for Efficient and Functional Protein Design.

Bioinformatics (Oxford, England) Apr 15, 2026

MOTIVATION: Although deep learning has accelerated protein design, current protein representations such as sequences or full-atom structures scale non-linearly with protein length. We propose a sparse and interpretable representation for proteins, ba... read more

Contrastive multimodal deep learning for survival prediction in grade 2/3 gliomas.

JNCI cancer spectrum Apr 15, 2026

BACKGROUND: Accurate survival prediction for grade 2/3 glioma patients remains challenging due to tumor biological heterogeneity and limitations of current prognostic methods that rely on single-modality data. METHODS: We developed a multimodal deep ... read more

Enhanced cortical connectivity during passive robotic-assisted gait training in individuals with spinal cord injury: An EEG study.

Gait & posture Apr 15, 2026

BACKGROUND: Robotic-assisted gait training (RAGT) has emerged as a promising strategy to promote neuroplasticity and motor recovery in individuals with spinal cord injury (SCI). This study investigates cortical connectivity during passive robotic gai... read more

Decoupling lactylation-associated metabolic remodelling in Asthma: Integrated multi-omics and machine learning identify RCC2 as a potential therapeutic target.

Computer methods and programs in biomedicine Apr 15, 2026

BACKGROUND: Aerobic glycolysis promotes lactate accumulation and histone lactylation (Kla), yet the cell-type-specific distribution of this axis and its link to metabolically stratified intercellular signalling in asthma remain poorly defined. We aim... read more

Construction and interpretability evaluation of a prediction model for radiographic pneumonia in children at outpatient and emergency departments.

International journal of medical informatics Apr 15, 2026

BACKGROUND: Radiographic confirmation is crucial for pediatric pneumonia diagnosis, but chest X-ray overuse in outpatient and emergency settings raises concerns about unnecessary radiation and resource utilization. This study aimed to develop and val... read more

Artificial Intelligence Medical Compendium