Regulatory toxicology and pharmacology : RTP
Apr 15, 2026
The development of new approach methodologies using machine learning offers promising alternatives to animal testing for toxicity assessment. However, to be suitable for regulatory use, machine learning models must ensure transparency and interpretab... read more
International journal of antimicrobial agents
Apr 15, 2026
OBJECTIVES: In this study, we developed an integrated approach for accurate and comprehensive prediction of anti-microbial resistance (AMR) using whole-genome sequencing (WGS) data. METHODS: We developed machine learning (ML) models using WGS data fr... read more
ETHNOPHARMACOLOGICAL RELEVANCE: Hypecoi Erecti Herba, derived from plants of the genus Hypecoum (Papaveraceae), includes two source species: Hypecoum leptocarpum Hook.f. & Thomson and Hypecoum erectum L. It is widely distributed across northern, nort... read more
Anti-arboviral peptides are biomolecules capable of interfering with key stages of the arboviral lifecycle. We present a dataset compiling 270 peptides composed of standard amino acids with reported activity against arboviruses, along with their leng... read more
AJR. American journal of roentgenology
Apr 15, 2026
BACKGROUND. Vision-language models (VLMs) have potential to identify findings on radiologic imaging (i.e., visual parsing) and translate findings into diagnoses (i.e., diagnostic reasoning). Current VLMs have shown insufficient performance to support... read more
Clinical cancer research : an official journal of the American Association for Cancer Research
Apr 15, 2026
PURPOSE: Cancers present significant DNA methylation changes, which arise in a stochastic manner, marked by extensive epigenetic variation, indicative of high epigenetic instability. We aimed to evaluate the utility of epigenetic instability for cell... read more
Cell therapies have demonstrated great potential for treating a broad range of diseases where conventional treatments have failed. However, long development times and sub-optimal processing conditions often hinder their clinical translation. To effic... read more
Biological inspiration offers new and innovative solutions to exploring challenging terrains, and implementations in bio-inspired robotics in turn offers insights to biological form and function. In particular, annelids (segmented worms), such asNere... read more
With the rapid expansion of smart cities and the growing need for accurate and real-time analysis of road infrastructure, the development of artificial intelligence systems capable of perceiving, analyzing, and recording environmental information has... read more
Computer methods and programs in biomedicine
Apr 14, 2026
BACKGROUND AND OBJECTIVE: Coronary artery disease (CAD) is a leading cause of mortality worldwide, underscoring the need for accurate and timely diagnosis. While X-ray coronary angiography remains the clinical gold standard for detecting stenosis, it... read more
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