European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
Apr 15, 2026
OBJECTIVES: Achieving a pathological complete response (pCR) following neoadjuvant chemoradiotherapy (nCRT) in patients with locally advanced rectal cancer (LARC) enables organ preservation and may obviate the need for radical surgery. This study aim... read more
RATIONALE AND OBJECTIVES: Differentiating benign from malignant thyroid nodules is particularly challenging in patients with Hashimoto's thyroiditis (HT), where inflammatory changes can mimic cancer. We developed a region-guided decoupled fusion netw... read more
The manual assessment of brain Magnetic Resonance Imaging (MRI) scans can be labor-intensive and time-consuming for radiologists. Deep Learning methods have demonstrated the potential to aid this process. However, their effectiveness relies on the av... read more
Exogenous substances (including additives and pollutants), as key factors influencing anaerobic digestion (AD) systems, exert dual effects on microbial activity, community structure, and metabolic function. This review systematically evaluates the ad... read more
BACKGROUND: Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival largely dependent on early detection. Standard-dose computed tomography (CT) screening, guided by the Lung Imaging Reporting and Data System (Lung-... read more
Filamentous bulking (FB) is a recurring cause of solids-separation failure in activated sludge systems. Standard diagnostics such as sludge volume index (SVI) and routine microscopy are largely reactive, confirming deterioration only after settling p... read more
Regulatory toxicology and pharmacology : RTP
Apr 15, 2026
The development of new approach methodologies using machine learning offers promising alternatives to animal testing for toxicity assessment. However, to be suitable for regulatory use, machine learning models must ensure transparency and interpretab... read more
International journal of antimicrobial agents
Apr 15, 2026
OBJECTIVES: In this study, we developed an integrated approach for accurate and comprehensive prediction of anti-microbial resistance (AMR) using whole-genome sequencing (WGS) data. METHODS: We developed machine learning (ML) models using WGS data fr... read more
ETHNOPHARMACOLOGICAL RELEVANCE: Hypecoi Erecti Herba, derived from plants of the genus Hypecoum (Papaveraceae), includes two source species: Hypecoum leptocarpum Hook.f. & Thomson and Hypecoum erectum L. It is widely distributed across northern, nort... read more
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.