JMIR bioinformatics and biotechnology
Apr 14, 2026
BACKGROUND: Autosomal dominant nonsyndromic hearing loss (ADNSHL) is highly heterogeneous, with more than 64 genes implicated in its etiology. This complexity limits the diagnostic power of clinical examinations and audiometry alone, while existing c... read more
BACKGROUND: Many people relapse after achieving abstinence in substance use disorders. Health care providers may scan the horizon for new technologies to predict response that allow interventions to be targeted rather than routine. Currently, no such... read more
Respiration; international review of thoracic diseases
Apr 14, 2026
INTRODUCTION: Obstructive sleep apnea (OSA) can cause severe complications if left untreated. Several challenges hinder OSA identification in females, resulting in underdiagnosis and undertreatment in this population. This study aimed to develop a ma... read more
Intraoperative hypotension (IOH) is a frequent occurrence during noncardiac surgery. Hypotensive episodes can compromise tissue perfusion, and cumulative exposure has been associated with adverse outcomes such as acute kidney injury (AKI), myocardial... read more
BACKGROUND: Cochrane plain language summaries (PLSs) aim to make systematic review findings more accessible to the general public. However, inconsistencies in how conclusions are presented may impact comprehension and decision-making. Classifying PLS... read more
Patients with diabetes mellitus-induced erectile dysfunction (DMED) usually suffer more severe symptoms, and efficacy of the first-line therapy is limited. This study develops an integrated framework combining single-cell RNA sequencing (scRNA-seq) a... read more
BACKGROUND: Images play an important role in reducing stigma related to mental health, which often is distorted in the media. In recent years, generative artificial intelligence (AI) has been used to generate images related to mental health. However,... read more
BACKGROUND: The integration of robotic systems into nursing practice is increasingly discussed as a potential strategy to alleviate workload and support care processes in response to demographic changes and staffing shortages. However, the acceptance... read more
Background: Long-term PM2.5 exposure is a major health risk, yet the heterogeneity of its chemical components and sources is often overlooked in risk assessments. Methods: Using county-level census data for 1990, 2000, and 2010 in China, we employed ... read more
BACKGROUND: Artificial intelligence-powered conversational agents (ie, chatbots) are increasingly popular outlets for users seeking psychological support, yet little is known about how users experience early-stage prototypes or which therapeutic proc... read more
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