Cognitive dysfunction is a common extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD). Here, we applied an XGBoost-SHAP machine learning framework to identify cortical morphological features related to cognitive performance i... read more
The interaction between T cell receptors (TCRs), peptides, and human leukocyte antigens (HLAs) underlies antigen-specific T cell immunity. Despite substantial advances in peptide-HLA presentation prediction, accurate modeling of coupled TCR-peptide-H... read more
What makes some stimuli more memorable than others? Recent work has shown that image memorability is predicted by the magnitude of population responses in both monkey inferotemporal cortex and convolutional neural networks, suggesting that stimuli th... read more
BACKGROUND: Current risk scores inadequately predict long-term mortality after transcatheter aortic valve replacement (TAVR), limiting their ability to guide decisions around procedural futility. We aimed to develop and externally validate a machine ... read more
BACKGROUND: Heterogeneity of heart failure with preserved ejection fraction (HFpEF) results in significant challenges for treatment development. Identifying and characterising distinct HFpEF phenogroups may aid in tailoring therapeutic strategies for... read more
Surgical oncology clinics of North America
Apr 10, 2026
Minimally invasive surgery has evolved from a disruptive concept to a cornerstone of modern surgical oncology. The integration of imaging, robotics and artificial intelligence (AI) has transformed surgical care into a highly data-driven, precise and ... read more
Sample Exploring the ocean environment holds profound significance in areas such as resource exploration and ecological protection. Underwater robots struggle with extreme water pressure and often cause noise and damage to the underwater ecosystem, w... read more
PDA journal of pharmaceutical science and technology
Apr 10, 2026
The European Qualified Person (QP) holds unique legal responsibility for certifying batch release, ensuring patient safety, and maintaining regulatory compliance. Modern pharmaceutical manufacturing-especially in biologics, advanced therapy medicinal... read more
PDA journal of pharmaceutical science and technology
Apr 10, 2026
Advanced technologies in both aseptic filling and environmental monitoring are coming together to improve the resilience and sterility assurance of aseptic processing. Continuous, real-time environmental monitoring using biofluorescent particle count... read more
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