AI Medical Compendium

Accurate and interpretable ADMET prediction: Integrating structural, geometric, and global molecular context representations.

European journal of medicinal chemistry Apr 9, 2026

Predicting absorption, distribution, metabolism, excretion, and toxicity (ADMET) profiles early in drug discovery is essential to avoid late-stage failures. However, most current computational models depend on single-view molecular representations. T... read more

GCI: A generative CT interpolation model for rapid wood CT scanning.

Micron (Oxford, England : 1993) Apr 9, 2026

Micro-computed tomography (micro-CT) is a key technique for acquiring three-dimensional images of materials, yet its long scanning and reconstruction time and high cost limit large-scale application. Fast scanning by varying pitch value to loss of im... read more

Optimization of Zanthoxylum bungeanum essential oil extraction based on response surface methodology and machine learning with activity evaluation.

Journal of chromatography. A Apr 9, 2026

This study extracted Zanthoxylum bungeanum essential oil via steam distillation, with the extraction process optimized using Response Surface Methodology (RSM) and machine learning techniques. The results indicated that the optimal conditions predict... read more

Multivariate machine learning regression approaches to predict adolescent suicide risk.

Psychiatry research Apr 9, 2026

BACKGROUND: Suicide is a leading cause of death among adolescents, yet most prediction models rely on binary classification and limited predictors, failing to capture the complexity of suicide risk. This study aimed to develop a more accurate and com... read more

Artificial intelligence in chest imaging beyond COVID-19: from hype to clinical utility.

Clinical imaging Apr 9, 2026

Regulatory risk loci link disrupted androgen response to the pathophysiology of polycystic ovary syndrome.

Journal of the Endocrine Society Apr 9, 2026

A major challenge in deciphering the complex genetic landscape of polycystic ovary syndrome (PCOS) lies in the limited understanding of how susceptibility loci drive molecular mechanisms across diverse phenotypes. To address this, we integrated molec... read more

Predicting sediment ecological state from metagenomes shows equal performance for taxonomic and functional features.

Marine environmental research Apr 9, 2026

The use of environmental microbial DNA to monitor the ecological state in seafloor sediments has many advantages and efforts are being made to find reliable biomarkers from DNA-based taxonomic profiles. However, the taxonomic composition of microbial... read more

Smart diagnostics: Leveraging artificial intelligence for accurate at-home COVID-19 testing.

Diagnostic microbiology and infectious disease Apr 9, 2026

Reverse transcriptase polymerase chain reaction (RT-PCR), the reference standard for COVID-19 diagnosis, is time-consuming, resource-intensive, and costly. Rapid antigen tests address these limitations but rely on visual interpretation, which may red... read more

Research progress in flap temperature monitoring technologies and applications after transplantation.

APL bioengineering Apr 9, 2026

As a primary method for tissue repair and functional reconstruction, flap transplantation has achieved a clinical success rate of over 90%. However, the postoperative incidence of vascular crisis remains as high as 10%-30%, making it a leading cause ... read more

Association of widespread pain and peak alpha frequency cannot be isolated to a single network.

Pain reports Apr 9, 2026

INTRODUCTION: Peak alpha frequency (PAF), an electroencephalography measure, has gained interest due to its association to pain-related neural processes in both healthy and clinical populations. In healthy groups, PAF derived from the sensorimotor co... read more

Artificial Intelligence Medical Compendium