Biological neural networks are characterized by short average path lengths, high clustering, and modular and hierarchical architectures. These complex network topologies strike a balance between local specialization and global synchronization via lon... read more
While single-cell foundation models (SCFMs) have shown promise across various downstream tasks, their generalization performance in label-scarce settings remains a critical bottleneck. The absence of systematic benchmarks for these low-resource scena... read more
N4-acetylcytidine (ac4C) is an ancient and highly conserved chemical marker found in all domains of life. Recent advancements in sequencing techniques have enabled the functional analysis of ac4C occurrence by accurately capturing its locations and l... read more
Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality worldwide, yet existing prognostic models incompletely capture its molecular heterogeneity. We developed an interpretable, attention-based multi-branch deep learning framework for ... read more
Hepatobiliary & pancreatic diseases international : HBPD INT
Apr 5, 2026
BACKGROUND: Accurately predicting long-term survival after liver transplantation (LT) remains a major clinical challenge. Tacrolimus intrapatient variability (Tac-IPV) has emerged as a potential prognostic marker, yet its integration into clinical de... read more
OBJECTIVES: This study aimed to validate an automated method for detecting tooth loss in intraoral scans (IOS) compared to clinical evaluations in a population-based sample. METHODS: 897 IOSs from 453 participants of the 1982 Pelotas Birth Cohort wer... read more
OBJECTIVES: To benchmark late-2025 general-purpose multimodal large language models (LLMs) on the Japanese National Dental Examination (JNDE) and to reassess a previously identified persistent-failure set. METHODS: GPT-5.2T, Claude 4.5, and Gemini 3 ... read more
Marine bivalves often face heavy metal stress, yet we still lack of high-resolution way to observe the metal pollution status in soft tissue. This study provides the first high-resolution spatial mapping of cadmium (Cd) and associated heavy metals in... read more
Machine learning (ML) in digital health applications is becoming more popular for the general management of population wellness and the promotion of large-scale prevention, risk stratification, and the use of data to formulate data-driven decision-ma... read more
Sudden shock loads in wastewater influent can severely disrupt biological treatment processes and cause effluent quality exceedances in wastewater treatment plants, particularly in domestic-industrial integrated facilities. Timely and reliable early ... read more
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