Stroke has a multifactorial etiology, and phthalates, as widely used environmental chemicals, may play an underexplored role in cerebrovascular health. This study aimed to evaluate the association between urinary phthalate metabolites and stroke risk... read more
OBJECTIVES: Approximately 6.9% of children in the United Kingdom have suffered physical abuse. Fractures are a common sign and must not be overlooked due to high recurrence and mortality rates. We aimed to train and assess the diagnostic accuracy of ... read more
OBJECTIVE: Accurate preoperative assessment of muscle invasion in bladder cancer (BCa) guides therapy selection. However, MRI interpretation varies across readers and lesion morphologies. Therefore, we aimed to overcome the morphology-associated diag... read more
OBJECTIVES: To investigate the value of machine learning classifiers incorporating dual-layer spectral CT (DLCT) parameters for preoperative prediction of spread through air spaces (STAS) in patients with lung adenocarcinoma. MATERIALS AND METHODS: T... read more
Journal of computer-aided molecular design
Apr 4, 2026
3-Mercaptopyruvate sulfurtransferase (3-MST), a key enzyme in sulfur metabolism, has recently gained attention as a potential anticancer target. However, reported 3-MST inhibitors remain limited, motivating the exploration of new scaffolds such as na... read more
OBJECTIVE: ACTH-dependent Cushing's syndrome (CS) causes profound immune dysfunction and severe infections. This study aimed to characterize immune cell phenotypes, develop predictive models for differentiating Cushing's disease (CD) from ectopic ACT... read more
Journal of chemical information and modeling
Apr 4, 2026
High-speed atomic force microscopy (HS-AFM) is a powerful technique for visualizing protein dynamics in real time at the single-molecule level and has enabled direct observation of diverse biomolecular processes such as protein conformational changes... read more
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