Systematists have long been fascinated by the astounding variation in species diversity across the various branches of the tree of life, a net result of the uneven rates at which lineages undergo speciation and extinction over time. The past 30 years... read more
The accurate characterization of species diversity is a vital prerequisite for ecological and evolutionary research, as well as conservation. Thus, it is necessary to generate robust hypotheses of species limits based on the inference of evolutionary... read more
Lateral gene transfer (LGT) has contributed to the genetic makeup of various eukaryotic lineages, yet its prevalence and long-term significance remain poorly understood, particularly for transfers between eukaryotes. Here, we investigate LGT across 2... read more
Background Cardiovascular adverse events (CVAEs) after chemoradiotherapy (CRT) for lung cancer are major concerns in Appalachia due to high rates of smoking and pre-existing cardiovascular diseases (CVD). The objectives of this study were to characte... read more
Background: Segmentation of the left ventricular myocardium, left ventricular cavity, and right ventricular cavity on short-axis cine cardiac magnetic resonance (CMR) images is essential for quantifying cardiac structure and function. However, existi... read more
High inpatient opioid exposure is associated with increased risk of persistent opioid use. Early identification of high-risk patients may improve opioid stewardship. We developed machine learning models to predict high opioid exposure during hospital... read more
Background: Transthyretin cardiomyopathy (ATTR-CM) is a progressive, potentially fatal disease requiring accurate risk stratification. Echocardiography is the first-line imaging modality, with AI-based tools increasingly applied for automated analysi... read more
Brain development follows a precisely regulated biological timetable, with defined periods of vulnerability increasingly recognized in congenital disorders affecting early brain development. This biological timing can be captured by the emerging conc... read more
Background: Extrauterine growth restriction (EUGR) is a common and clinically significant complication among preterm infants, contributing to adverse neurodevelopmental and metabolic outcomes. Early and individualized risk prediction remains challeng... read more
During the COVID-19 pandemic, reported incidence data played a central role in public health surveillance and in tracking epidemic dynamics, although they provide limited insight into the behavioral, immunological, and socioeconomic drivers of transm... read more
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