Tumor tissue engineering, integrating organoid, microfluidic, and biofabrication technologies, has opened new avenues for cancer research. Leveraging advanced bioengineering and biomaterials, these 3D models capture tumor architecture, cellular heter... read more
Artificial intelligence has rapidly advanced molecular science, yet progress has largely unfolded through specialized models tailored to specific tasks. In this issue of Cell, Peng et al. introduce PocketXMol, a unified 3D generative framework that r... read more
Single-cell assay for transposase-accessible chromatin with sequencing (scATAC-seq) enables investigation of open chromatin landscapes at single-cell resolution. However, analyzing scATAC-seq data remains challenging due to inherent sparsity and nois... read more
The Journal of thoracic and cardiovascular surgery
Apr 2, 2026
BACKGROUND: We implemented a prospective screening program to detect deep venous thromboembolism and define its prevalence in patients with esophageal cancer undergoing esophagectomy. We sought to delineate contributions of the underlying cancer and ... read more
The severe environmental and health risks posed by perfluoroalkyl substances (PFASs), coupled with the limitations of conventional detection methods, have highlighted the urgent need to develop efficient analytical platforms. However, the simultaneou... read more
DNA microarray is a transformative technique in genomics, enabling simultaneous examination of thousands of gene expression levels. However, noise, high dimensionality (typically 12,000-22,000 genes), small sample sizes (155-1097 samples) and class i... read more
Journal of chemical information and modeling
Apr 2, 2026
σ-Profiles obtained from quantum-chemical calculations are key molecular descriptors for solvent selection, thermodynamic modeling, and data-driven molecular design. However, existing σ-profile libraries are limited in size and are difficult to combi... read more
Multidimensional tea profiling is crucial for consumer experience, brand reputation, and market integrity. Here, we introduce a rapid and systematic strategy for multidimensional tea authentication based on a single surface-enhanced Raman spectroscop... read more
Modern cardiology is entering a phase where improving the prevention, diagnosis, and treatment of cardiovascular diseases (CVD) necessitates a deeper understanding of the underlying biological mechanisms. The traditional clinical model, relying prima... read more
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