Predicting pathological complete response (pCR) to neoadjuvant therapy (NAT) in breast cancer remains challenging due to high tumor heterogeneity and disparities across data modalities. This study introduces a multimodal learning framework that integ... read more
INTRODUCTION: Melanoma and Breast cancer are the leading cancers that cause thousands of deaths annually worldwide. Although several early identification methods and treatments are being used, they have limitations, such as drug resistance and off-ta... read more
CNS & neurological disorders drug targets
Apr 2, 2026
A revolutionary method for targeted neurotherapeutics is focused ultrasound (FUS)-mediated blood-brain barrier (BBB) regulation. In order to enable controlled and targeted intracerebral drug delivery, recent developments in hybrid extracellular vesss... read more
BACKGROUND: Compared with conventional colonoscopy, computer-assisted adenoma detection (CADe) colonoscopy and Endocuff-Vision (EV) have been shown to increase the adenoma detection rate (ADR). However, the evidence for whether their combination furt... read more
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
Apr 2, 2026
BACKGROUND AND AIMS: Artificial intelligence (AI) tools, including large language models (LLMs) such as ChatGPT, Claude, and Gemini, are increasingly used in biomedical research. However, practical guidance for integrating these tools into the manusc... read more
BACKGROUND: Predicting response to immune checkpoint inhibitor plus tyrosine kinase inhibitor (IO+TKI) therapy in metastatic renal cell carcinoma (mRCC) remains challenging. Forkhead box protein O1 (FOXO1) is a key transcription factor regulating tum... read more
Sludge settleability characterized by the sludge volume index (SVI) is essential in assessing the operational stability of wastewater treatment systems. However, previous studies primarily focus on correlations between features and SVI in single wast... read more
Clinics and research in hepatology and gastroenterology
Apr 2, 2026
BACKGROUND: In individuals with normal body weight, altered fat distribution contributes to metabolic dysfunction and hepatic steatosis. We hypothesized that the weight-adjusted waist index (WWI), an indicator of abdominal fat accumulation, is associ... read more
BACKGROUND: The adoption of artificial intelligence (AI) scribes has grown rapidly in recent years, aiming to improve clinical workflow, increase efficiency, and reduce administrative burden by transcribing doctor-patient interactions. These systems ... read more
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