AI Medical Compendium

Co-repression of Yap1 and Sox9 Abrogates Established Cholangiocarcinoma by Eliminating Transcriptional Compensation.

Clinical and molecular hepatology Apr 3, 2026

BACKGROUND/AIMS: Intrahepatic cholangiocarcinoma (iCCA) represents an unmet clinical need due to its increasing incidence, aggressive biology, and limited treatment options. The extremely low-response rates to current systemic regimens and the emerge... read more

Interpretable Machine Learning to Understand Wildfire Toxicity: Bridging Chemicals, Omics, and Toxicological Outcomes via Symbolic Regression with Novel Feature Scoring.

Chemical research in toxicology Apr 3, 2026

Wildfire smoke exposures are increasingly common, consisting of complex mixtures of gases and particulates known to cause diverse pulmonary health effects. While health outcomes are regularly studied, quantitative links between smoke chemical composi... read more

Acute spinal cord injury: contemporary management and novel therapies.

Asian spine journal Apr 3, 2026

Acute spinal cord injury (SCI) remains a life-threatening condition associated with substantial morbidity, mortality, and long-term disability. Despite the advances in trauma systems, surgical techniques, and critical care, the optimal management str... read more

Comprehensive multi-method analysis of blood heavy metals and nutrient intake in myopia and high myopia.

Journal of translational medicine Apr 3, 2026

Determination of Trichomonas vaginalis, certain bacterial and fungal positivity, and risk factors in female patients with urinary and genital complaints.

BMC infectious diseases Apr 3, 2026

An Evolving View of Lineage Diversification.

Systematic biology Apr 3, 2026

Systematists have long been fascinated by the astounding variation in species diversity across the various branches of the tree of life, a net result of the uneven rates at which lineages undergo speciation and extinction over time. The past 30 years... read more

Integrating Genomics, Collections, and Community Science to Delimit Species Clarifies the Taxonomy of a Variable Monitor Lizard (Varanus tristis).

Systematic biology Apr 3, 2026

The accurate characterization of species diversity is a vital prerequisite for ecological and evolutionary research, as well as conservation. Thus, it is necessary to generate robust hypotheses of species limits based on the inference of evolutionary... read more

Cardiovascular Adverse Events After Definitive Chemoradiotherapy for Lung Cancer in an Appalachian Population: Incidence and Machine Learning Based Prediction

medRxiv Apr 3, 2026

Background Cardiovascular adverse events (CVAEs) after chemoradiotherapy (CRT) for lung cancer are major concerns in Appalachia due to high rates of smoking and pre-existing cardiovascular diseases (CVD). The objectives of this study were to characte... read more

oncology

CorSeg-CineSAX: An Open-Source Deep Learning Framework for Fully Automatic Segmentation of Short-Axis Cine Cardiac MRI Across Multiple Cardiac Diseases

medRxiv Apr 3, 2026

Background: Segmentation of the left ventricular myocardium, left ventricular cavity, and right ventricular cavity on short-axis cine cardiac magnetic resonance (CMR) images is essential for quantifying cardiac structure and function. However, existi... read more

cardiovascular medicine

Machine learning-based prediction model for risk factors associated with conversion to open surgery in pediatric laparoscopic radical resection of choledochal cysts.

Pediatric surgery international Apr 3, 2026

Artificial Intelligence Medical Compendium