Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Apr 3, 2026
BACKGROUND: Cone-beam computed tomography (CBCT) is widely used in dentomaxillofacial imaging and radiotherapy but is limited by noise and low contrast resolution. Deep learning (DL) has emerged as a promising tool for CBCT enhancement, improving ima... read more
MOTIVATION: Although deep learning has significantly advanced the field of protein function prediction, current approaches are limited by their reliance on a narrow set of modalities. Specifically, they primarily rely on sequence patterns and treat p... read more
OBJECTIVE: To systematically evaluate the contribution of clinical heterogeneity to chronic kidney disease (CKD) progression in gout patients using data-driven phenotyping, and to assess whether incorporating genetic risk improves prediction of renal... read more
Functional peptide discovery, particularly for blood-brain barrier-penetrating peptides (BBBPPs), is strictly limited by extreme data scarcity and the "black-box" nature of deep learning. Here, INB3P is presented as a physics-informed, multi-modal fr... read more
Journal of diabetes science and technology
Apr 3, 2026
BACKGROUND: One of the most common consequences in individuals with diabetes is the diabetic foot, which can cause foot ulcers and even lead to limb amputation. Since an increase of the temperature in the plantar region is directly correlated with an... read more
Lateral gene transfer (LGT) has contributed to the genetic makeup of various eukaryotic lineages, yet its prevalence and long-term significance remain poorly understood, particularly for transfers between eukaryotes. Here, we investigate LGT across 2... read more
Bioactive peptides derived from dairy proteins are increasingly recognized for their dual capacity to enhance sensory attributes and provide health-promoting functions. In fermented dairy products such as yogurt, proteolysis releases a diverse array ... read more
Staphylococcus aureus is a leading cause of intramammary infections (IMI) in Canadian dairy herds and is frequently isolated from both clinical and subclinical mastitis cases. Persistent IMI caused by S. aureus are of particular concern, as they are ... read more
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