AI Medical Compendium

Proteome-Wide Structural and Interaction Analysis Using Cross-Linking Mass Spectrometry and its Applications.

Biophysical journal Apr 2, 2026

Deciphering the mechanisms of protein-protein interactions (PPIs) and protein structural changes within the native cellular environment is crucial for advancing drug discovery. In-vivo chemical cross-linking coupled with mass spectrometry (XL-MS) cap... read more

Modified ShuffleNet trained on gradient pattern and shape-based features for lung cancer classification with improved M-SegNet segmentation.

Scientific reports Apr 2, 2026

Lung cancer (LC) is one of the leading causes of death globally. Early detection is essential for saving lives and ensuring effective treatment for patients. When medical professionals can proactively diagnose and classify the condition, they can pro... read more

Machine learning in the prediction of liver iron concentration and iron chelation therapy adjustment.

Hematology (Amsterdam, Netherlands) Apr 2, 2026

OBJECTIVES: Iron chelation therapy titration is managed by hematologists who monitor iron levels and adjust medication dosages to achieve patient outcomes. This study developed a machine learning (ML) algorithm to predict the liver iron concentration... read more

An explainable online frailty prediction model for community-dwelling older adults based on machine learning algorithms: a cross-sectional study based on retrospective health data.

Annals of medicine Apr 2, 2026

BACKGROUND: Frailty is a significant health concern associated with diminished physiological reserves and increased healthcare burdens. Currently, effective models for predicting frailty risk are lacking. This study utilizes machine learning-based mo... read more

AI foundation models for RNA biology.

RNA biology Apr 2, 2026

RNA biology is undergoing a transformative revolution driven by AI foundation models. These models learn the intricate relationships between RNA sequence, structure, and function by training on vast, diverse datasets spanning millions of RNA molecule... read more

Machine learning triumphs in differentiating fungal and bacterial infections.

BMC infectious diseases Apr 2, 2026

Polymer Drug Conjugate: A Revolution in Drug Delivery.

AAPS PharmSciTech Apr 2, 2026

Polymer-drug conjugates (PDCs) represent a remarkable advancement in modern medicine, leveraging the physicochemical properties of polymers to enhance the efficacy and safety of therapeutic agents. This comprehensive review explores the historical ev... read more

A visual perceptual perspective on gaze in social robotics.

Psychonomic bulletin & review Apr 2, 2026

Where and when should a robot look during interaction with humans? Intuitively, human-human interaction serves as the blueprint. In such interactions, gaze plays a central role, both in visually guiding action and in signaling communication. Yet, mos... read more

Artificial Intelligence-Guided Optimization of Hyaluronic Acid-Coated Liposomal Linagliptin for Targeted Management of Polycystic Ovary Syndrome.

AAPS PharmSciTech Apr 2, 2026

Linagliptin, a DPP-4 inhibitor commonly used in the management of diabetes mellitus, has shown potential activity in polycystic ovary syndrome (PCOS). Linagliptin's therapeutic effectiveness is limited by its poor membrane permeability and low oral b... read more

Long-term prognostic implications of AI-detected versus AI-undetected breast cancers on mammography: a propensity score-matched analysis.

European radiology Apr 2, 2026

OBJECTIVES: To evaluate the association between the cancer detectability by artificial intelligence (AI) and long-term survival outcomes in invasive breast cancer. MATERIALS AND METHODS: This retrospective study analyzed consecutive women diagnosed w... read more

Artificial Intelligence Medical Compendium