Long-tailed classification, where a small number of frequent classes dominate many rare ones, remains challenging because models systematically favor frequent classes at inference time. Existing post-hoc methods such as logit adjustment address this ... read more
High inpatient opioid exposure is associated with increased risk of persistent opioid use. Early identification of high-risk patients may improve opioid stewardship. We developed machine learning models to predict high opioid exposure during hospital... read more
Background: Accurate preoperative prediction of lymph node metastasis (LNM) in papillary thyroid carcinoma (PTC) remains challenging, particularly in clinically node-negative (cN0) patients, leading to potential overtreatment. We aimed to develop and... read more
Background: Transthyretin cardiomyopathy (ATTR-CM) is a progressive, potentially fatal disease requiring accurate risk stratification. Echocardiography is the first-line imaging modality, with AI-based tools increasingly applied for automated analysi... read more
During the COVID-19 pandemic, reported incidence data played a central role in public health surveillance and in tracking epidemic dynamics, although they provide limited insight into the behavioral, immunological, and socioeconomic drivers of transm... read more
Background: Extrauterine growth restriction (EUGR) is a common and clinically significant complication among preterm infants, contributing to adverse neurodevelopmental and metabolic outcomes. Early and individualized risk prediction remains challeng... read more
Brain development follows a precisely regulated biological timetable, with defined periods of vulnerability increasingly recognized in congenital disorders affecting early brain development. This biological timing can be captured by the emerging conc... read more
Selecting an effective treatment relies on accurately anticipating patient's response to alternative interventions. However, forecasting longitudinal clinical trajectories remains difficult because electronic health records contain heterogeneous, irr... read more
Lupus nephritis (LN) represents the most severe renal manifestation of systemic lupus erythematosus (SLE), contributing to significant morbidity. While current assessments focus on glomerular pathology, tubulointerstitial lesions may offer critical i... read more
Neural networks : the official journal of the International Neural Network Society
Apr 2, 2026
RNA-binding proteins (RBPs) regulate post-transcriptional gene expression by recognizing specific RNA elements, making accurate identification of RBP binding sites essential for understanding gene regulation and disease mechanisms. However, experimen... read more
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