CPT: pharmacometrics & systems pharmacology
Apr 1, 2026
Tumor dynamic models are vital for evaluating oncology treatments and guiding clinical drug development decisions. However, few studies rigorously assess their predictive capabilities, especially when forecasting tumor trajectories from clinical tria... read more
Deconvolution beamforming maintains robustness against array mismatch and limited snapshots in underwater source localization, yet its resolution and accuracy require improvement. Inspired by deep learning architectures, this work proposes a multi-la... read more
Seasonal variability in sperm whale acoustic activity in the northern Gulf of Mexico remains poorly understood. Using two years of passive acoustic data, hourly click counts were analyzed to characterize seasonal patterns in whale presence and behavi... read more
Purpose To assess the prognostic value of deep learning-derived radiographic age and aging velocity for predicting mortality in an Asian cohort. Materials and Methods This retrospective cohort study included Korean adults who underwent posteroanterio... read more
This Focus Issue forms one part (NDS-G) of the Double Focus Issue on nonautonomous dynamical systems in the sciences that was published together with a second Focus Issue on nonautonomous dynamical systems in climate (NDS-C). Nonlinear dynamics has a... read more
PURPOSE: To determine whether rates of change in lamina cribrosa (LC) depth and curvature in POAG patients are associated with rates of visual field (VF) progression. METHODS: We used 24 radial B-scan spectral domain optic coherence tomographic image... read more
INTRODUCTION: Large language models (LLMs) are increasingly being explored in healthcare, particularly for enhancing patient education. In spine surgery, LLMs have the potential to enhance communication and support patients through perioperative care... read more
CONTEXT: Effective communication of complex medical information is critical for individuals with spinal cord injury (SCI) and their families, but this need remains largely unmet. Artificial intelligence (AI), including large language models (LLMs) li... read more
Despite the initial success of EGFR-targeted therapies in non-small cell lung cancer (NSCLC), the emergence of drug resistance remains a significant clinical challenge. While several approved anticancer drugs exist, the development of resistance to c... read more
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