AI Medical Compendium

GATv2-TransDTI: A graph and sequence hybrid model for fine-grained drug-target interaction prediction.

Analytical biochemistry Apr 1, 2026

Accurately predicting drug-target interaction (DTI) is critical for drug discovery and development. Existing methods typically rely on the atomic structure or molecular graphs of drugs, along with amino acid sequences of target proteins, to extract f... read more

Incubating artificial intelligence initiatives and careers in dermatology.

The Journal of investigative dermatology Apr 1, 2026

Explainable machine learning to predict muscle loss during radiotherapy for oral cavity cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology Apr 1, 2026

BACKGROUND AND PURPOSE: Muscle loss during adjuvant radiotherapy is associated with poor survival outcomes in patients with oral cavity cancer (OCC). This study aimed to develop and validate an explainable machine learning model to predict muscle los... read more

Artificial intelligence uncovers latent signals of portal hypertension in routine CT imaging.

Journal of hepatology Apr 1, 2026

EEG-AI: An agentic system for AI-assisted semi-automated EEG preprocessing and artifact removal.

Journal of neuroscience methods Apr 1, 2026

BACKGROUND: EEG is widely used to identify neural markers, personalize treatments, and evaluate interventions. However, low signal-to-noise ratio and mixing of artifactual distorted interpretation. Traditional preprocessing approaches, including Inde... read more

Exploring the role of reinforcement learning in vision-language models for cardiovascular disease decision support.

Journal of biomedical informatics Apr 1, 2026

OBJECTIVE: To explore the role of reinforcement learning (RL) in vision-language models (VLMs) for cardiovascular disease (CVD) decision support and assess whether RL-enhanced multimodal reasoning improves clinical classification performance and inte... read more

Arterial pulse harmonic alterations: a novel biomarker linking vascular dysfunction to prefrailty.

Experimental gerontology Apr 1, 2026

BACKGROUND AND AIMS: The identification of prefrailty, a reversible state of vulnerability in older adults, remains a clinical challenge. Arterial stiffness-a hallmark of vascular aging-has been implicated in frailty, suggesting shared pathophysiolog... read more

AI-based segmentation of gingival display for gummy smile assessment: Model development and clinical validation.

Journal of dentistry Apr 1, 2026

OBJECTIVES: This study aimed to develop and validate an artificial intelligence (AI)-based model for quantitatively assessing gingival display during smiling using standardized extraoral photographs. The goal was to establish an objective and reprodu... read more

Classification of depressed and non-depressed MCI and non-depressed cognitively normal individuals using resting-state metrics: A multi-group study with machine learning and graph reinforcement learning.

Journal of affective disorders Apr 1, 2026

Depressive symptoms frequently co-occur in individuals with Mild Cognitive Impairment (MCI) and are thought to accelerate neurodegenerative progression. However, the underlying neural mechanisms of Depressed MCI (DMCI) remain largely unclear. This st... read more

Improving transthyretin cardiac amyloidosis detection from electrocardiograms through the Willem artificial intelligence platform.

Heart rhythm Apr 1, 2026

BACKGROUND: Transthyretin amyloid cardiomyopathy (ATTR-CM) is a frequently underdiagnosed disease in which delay in diagnosis limits the efficacy of treatments. Artificial intelligence (AI) applied to standard 12-lead electrocardiograms (ECGs) is pro... read more

Artificial Intelligence Medical Compendium