Precision neuroimaging aims to deliver individualized assessments of brain health, yet a single structural MRI does not yield a multidimensional, quantitative summary of an individual's current health or future risk. Existing approaches optimize task... read more
Abstract Background: Cardiovascular disease is the leading cause of mortality in Nigeria and across sub-Saharan Africa, with rising incidence attributable to urbanisation, sedentary lifestyles, and limited access to early detection tools. Concurrentl... read more
As climate change intensifies, health risks from extreme heat are rising. Accurate assessment of heat vulnerability at high spatial resolution is crucial for developing effective adaptation strategies, particularly in socioeconomically heterogeneous ... read more
Purpose: To evaluate whether chest radiograph-derived age acceleration is associated with incident lung cancer and whether it improves discrimination beyond established lung cancer risk factors. Materials and Methods: This retrospective analysis used... read more
Sepsis can lead to acute respiratory distress syndrome (ARDS) and is associated with a high mortality rate. This study investigated cellular senescence-related genes in sepsis and sepsis-induced ARDS to identify novel biomarkers. Using bioinformatics... read more
Background: Women with severe aortic stenosis (AS) are diagnosed later and experience poorer outcomes than men, partly because clinical approaches rely on 2D, valve-centric thresholds derived from male-predominant cohorts that underutilize informatio... read more
The rapid advancement of AI research automation systems--including AI Scientist, data-to-paper, and Agent Laboratory--has demonstrated the potential for autonomous scientific discovery. However, existing benchmarks for evaluating these systems focus ... read more
Biological staging models are a key tool for assessing the severity of Alzheimer's disease (AD), supporting personalized medicine and playing a critical role in clinical trial design. Recently, researchers have leveraged positron emission tomography ... read more
Background: Atopic dermatitis (AD) is a prevalent chronic inflammatory skin disease associated with clinical, psychosocial, and economic burden. Accurate severity assessment is essential for guiding treatment escalation and monitoring disease activit... read more
Objective: Behavioral and social factors (BSFs) substantially influence the risk, onset, and progression of Alzheimer disease and related dementias (ADRD). A systematic representation of their interplay is essential for advancing prevention and targe... read more
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