Photoacoustic Computed Tomography (PACT) leverages the photoacoustic effect for high-resolution anatomical and molecular imaging. We developed an advanced PACT system using eight conventional linear arrays arranged in a half-ring geometry, achieving ... read more
OBJECTIVE: This study aimed to develop and validate an ultrasound (US)-based deep transfer learning radiomics model, integrated with explainable machine learning, for the preoperative malignant risk prediction of parotid gland tumors (PGTs). METHODS:... read more
OBJECTIVES: In primary healthcare research, there are core challenges such as data silos and missing data. Furthermore, the current high technical barriers severely limit effective cross-regional data analysis. METHODS: This work was the first to app... read more
OBJECTIVE: The study aims to develop an artificial intelligence (AI) framework for automatic pressure injury (PI) staging directly from raw clinical images, without requiring manual lesion localisation. By integrating a two-stage deep learning approa... read more
OBJECTIVES: Suicide risk assessments currently rely on subjective clinical judgement, lacking objective measures. This study aimed to evaluate the association between biomarkers and suicide risk and to explore their predictive potential using machine... read more
Journal of neurology, neurosurgery, and psychiatry
Mar 27, 2026
BACKGROUND: Apathy, depression and anhedonia are clinically overlapping constructs, which hinders diagnostic clarity and treatment development. This study aimed to comprehensively characterise these syndromes to identify a core set of non-redundant s... read more
Journal of neurology, neurosurgery, and psychiatry
Mar 27, 2026
BACKGROUND: We aimed to evaluate the impact of implementing an artificial intelligence (AI)-enabled acute ischaemic stroke triage system on workflow efficiency and transfer optimisation in a large academic healthcare network. METHODS: A prospectively... read more
Bridging integrator 1 (BIN1) is one of the strongest genetic risk factors for Alzheimer's disease (AD), yet its function in the brain and role in AD remain unclear. Neuronal BIN1 isoform levels are decreased in AD, and recent data show an important r... read more
MOTIVATION: Single-cell RNA sequencing (scRNA-seq) data analysis is often performed using network projections that produce co-expression networks. These network-based algorithms are attractive because regulatory interactions are fundamentally network... read more
Spatial multi-omics enables the exploration of tissue microenvironments and heterogeneity from the perspective of different omics modalities across distinct spatial domains within tissues. To jointly analyze the spatial multi-omics data, computationa... read more
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