Proceedings of the National Academy of Sciences of the United States of America
Mar 27, 2026
Microbial communities play essential roles in shaping ecosystem functions and predictive modeling frameworks are crucial for understanding, controlling, and harnessing their properties. Competition and cross-feeding of metabolites drives microbiome d... read more
OBJECTIVE: To explore the relationship between Frailty Index (FI) and Knee osteoarthritis (KOA) in Chinese people aged 45 and above. METHODS: Data on symptomatic KOA, FI, and over ten covariates were from the China Health and Retirement Longitudinal ... read more
Accurate traffic flow prediction is essential for alleviating urban congestion, improving road network efficiency, and sup-porting sustainable transportation systems. Existing spatio-temporal graph neural networks, however, often struggle to capture ... read more
Large language models (LLMs) have demonstrated strong capabilities in semantic understanding and text generation. However, their direct application in the segmented and specialized domains of small and medium-sized enterprises (SMEs) presents several... read more
Autonomous Aerial Vehicles (AAVs) - known as drones - employment in delivery services is one of the promising transformative technologies. The AAV industry has taken significant steps to develop drones to fulfill the needs of delivery services. Howev... read more
Journal of chemical information and modeling
Mar 27, 2026
Small-molecule drug discovery requires balancing potency, selectivity, solubility, safety, and synthetic feasibility, among other interdependent properties. Yet most computational workflows address these properties sequentially or collapse them into ... read more
Prostate cancer (PCa) remains a major global health burden, with incidence rising as populations age. The molecular, histological, and patient-specific heterogeneity of PCa underscores the urgent need for advanced strategies to improve detection and ... read more
OBJECTIVES: Clarification of the strengths and weaknesses of cognitive ability is essential to our understanding of the characteristics of autism spectrum disorder and attention deficit/hyperactivity disorder. However, whether individuals with these ... read more
BACKGROUND: Tuberculosis remains a major global health challenge, particularly in resource-limited settings where access to expert radiological interpretation is constrained. Artificial intelligence offers a promising solution to enhance diagnostic a... read more
Studies of human social behavior indicate stronger social affinity in matched-neurotype dyads (e.g., two individuals with autism or two without) compared to mixed-neurotype dyads (e.g., one individual with autism paired with one without). Is this dya... read more
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