AI Medical Compendium

Immune gene MMP9 as a potential key mediator in TCDD exposure-associated atherosclerosis: An integrated study based on network toxicology and experimental validation.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association Mar 25, 2026

BACKGROUND: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a highly toxic, recalcitrant persistent organic pollutant with ubiquitous environmental distribution. Atherosclerosis (AS) is a systemic vascular disorder characterized by chronic vascular inf... read more

Subtypes estimation in single-cell multi-omics data via S-multi-SNE.

Journal of theoretical biology Mar 25, 2026

Single-cell RNA sequencing (scRNA-seq) has rapidly become an essential method in modern biology, as it allows global characterisation of transcriptomics in individual cells from different tissues, or organisms. scRNA-seq data are collected from a sin... read more

Decoding brain-heart dynamics: Effective connectivity predictors of heart rate variability.

NeuroImage Mar 25, 2026

Autonomic dysregulation characterizes neuropsychiatric and somatic disorders, often reflecting disrupted brain-heart communication mediated by the Central Autonomic Network (CAN). The CAN integrates visceral inputs and cortical control to maintain au... read more

Hippocampal-parietal directed connectivity mediates brain network reconfiguration between internal and external attention: An intracranial EEG study.

NeuroImage Mar 25, 2026

Attention is a cornerstone of cognitive function, and understanding its neural mechanisms is of great significance for both cognitive science and clinical applications. A critical aspect of this endeavor involves elucidating how the brain's network a... read more

Artificial Intelligence Decision Support in Screening Digital Breast Tomosynthesis: Evidence Before Enthusiasm.

Journal of the American College of Radiology : JACR Mar 25, 2026

Artificial Intelligence Dataset Enrichment in Lung Cancer Screening Research: Reader Versus Teacher.

Journal of the American College of Radiology : JACR Mar 25, 2026

Machine Learning Models Used to Predict Abdominal Aortic Aneurysm Growth and Rupture: A Systematic Review and Critical Appraisal.

Annals of vascular surgery Mar 25, 2026

BACKGROUND: Abdominal aortic aneurysm (AAA) rupture remains a major cause of mortality, and diameter-based surveillance is an imperfect predictor of risk. Some aneurysms rupture below operative thresholds, whereas others remain stable despite exceedi... read more

An Artificial Intelligence Application for Standardized Expert-Level Interpretation of Vascular Clinical Practice Guidelines.

Annals of vascular surgery Mar 25, 2026

BACKGROUND: Clinical practice guidelines (CPGs) are often complex and subject to the reader's interpretation. The aim was to develop and validate an artificial intelligence (AI)-driven application for standardized interpretation of CPGs. The applicat... read more

Quantitative regression of qFibrosis with resmetirom: Exploratory histologic endpoints from the MAESTRO-NASH phase III clinical trial.

Journal of hepatology Mar 25, 2026

BACKGROUND & AIMS: Resmetirom, a thyroid hormone beta (THR-β) agonist, has been shown to improve metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis in patients with non-cirrhotic MASH in a phase III serial liver biopsy study. In the... read more

Preliminary appraisal of machine learning based prediction models.

Journal of clinical epidemiology Mar 25, 2026

A significant portion of healthcare research is devoted to the development of prediction models, yet the integration of these models into routine clinical care remains limited. Persistent barriers, such as insufficient reporting, limited generalizabi... read more

Artificial Intelligence Medical Compendium