In computer-assisted diagnostics, assessing the quality of retinal images, especially for DR, is vital. While current Image Quality Assessment (IQA) methods lean on Transfer Learning (TL), their adaptability to specific IQA demands, especially for DR... read more
Hematopoietic stem cell (HSC)-targeted gene editing holds significant potential for treating hereditary hematopoietic disorders, yet the efficient and safe delivery of gene-editing tools into HSCs remains a critical challenge. Lipid nanoparticles (LN... read more
It is imperative to identify patients with prostate cancer (PCa) who will not benefit from androgen receptor signaling inhibitors and to improve their clinical outcomes. Using artificial intelligence (AI), in this multicenter cohort study of 623 PCa ... read more
Metabolism: clinical and experimental
Mar 24, 2026
BACKGROUND: Identifying high-risk individuals for cardiovascular and all-cause mortality among individuals with cardiovascular-kidney-metabolic (CKM) syndrome stage 0-3 can guide the implementation of targeted interventions. This study aimed to evalu... read more
Journal of neuroradiology = Journal de neuroradiologie
Mar 24, 2026
PURPOSE: To evaluate the utility of deep learning-based reconstruction (DLR) three-dimensional T1-weighted imaging (T1-WI) in improving fine structural delineation through the automated estimation of brain morphometry and perivascular space (PVS). MA... read more
Efficiently predicting drug synergy is crucial for developing personalized cancer combination therapy regimens. However, existing methods primarily focus on single-scale structural information and fail to explicitly model the interactions between mul... read more
Animal models are essential for studying aversive states such as fear and pain. Facial expressions may provide non-invasive readouts of aversive states in animals. This study investigated whether changes in facial expressions, which are potentially c... read more
STATEMENT OF PROBLEM: Cone beam computed tomography (CBCT) scans acquired with interocclusal separation improve stability and reduce motion artifacts but lack reliable occlusal contacts. Accurately reconstructing occlusion is critical for diagnosis, ... read more
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